Atypical Teratoid Rhabdoid Tumor in a Newborn: Can IVF Be a Risk Factor?

Abstract

Background

In recent years, with the widespread use of assisted reproductive technologies, questions have arisen regarding the possible relationship between these infertile parents with assisted conception procedures and childhood cancers. Case report: We present a 23-day-old newborn conceived by in vitro fertilization (IVF) with a 53 × 46 × 38 mm intracranial mass detected by magnetic resonance imaging on the 15th postnatal day. The mass, removed on 23rd postnatal day, was an Atypical Teratoid Rhabdoid Tumor (ATRT), WHO grade 4. Conclusions: As far as we know, this is the only neonatally detected ATRT. Further studies are needed to investigate whether there is a causal relationship between IVF and childhood cancers.

Keywords:

• Atypical teratoid rhabdoid tumor
• in vitro fertilization
• newborn

Disclosure statement

All authors have no funding or conflict of interest relevant to this article.