Inflammatory Myofibroblastic Tumor of the Sigmoid Colon in an Infant: A Case Report and Literature Review

Abstract

Background:

Inflammatory myofibroblastic tumor (IMT) infrequently involves the sigmoid colon, and has not previously been described in an infant sigmoid colon.

Case report:

An inflammatory myofibroblastic tumor arose from the sigmoid colon of an 11-month-old boy, confirmed by anaplastic lymphoma kinase (ALK), smooth muscle actin (SMA) and desmin immunohistochemical staining. The patient recovered well after complete resection of the tumor.

Discussion:

Sigmoid IMT can occur in infancy. This eighth case is the youngest so far. The child did well after surgical resection.

Keywords:

• Case report
• diagnosis
• inflammatory myofibroblastic tumor
• pathology
• sigmoid colon

Acknowledgements

We thank the patient and his family for their contribution.

Declaration of interest statement

The authors declare that they have no competing interests.

Ethical approval and consent to participate

The study was conducted in accordance with the Helsinki Declaration and its later amendments or comparable ethical standards.

Consent for publication

Informed written consent was obtained from the patient’s mother for publication of this case report and accompanying images.

Availability of data and materials

Not applicable.

Additional information

Funding

National Natural Science Foundation of China under Grant number 81873541 and the Sanming Project of Medicine in Shenzhen under Grant number SZSM201812055.