A Two-in-One Tumor in the Adrenal: A Functional Adrenocortical Adenoma with Myelolipomatous Differentiation

Abstract

Background

Adrenocortical adenoma (ADA) and myelolipoma are two common benign neoplasms of the adrenal cortex that have been reported to occur together.

Case report

A 14-year-old girl presented with the features of ACTH-independent endogenous Cushing syndrome. Abdominal CECT revealed a left adrenal 2.3 × 1.8 × 1.5 cm arterially enhancing nodular lesion with central hypodensity. Histologically, this was an ADA with oncocytic change and myelolipomatous differentiation/metaplasia.

Discussion/Conclusion

ADA with myelolipomatous differentiation/metaplasia can occur in the pediatric age group.

Keywords:

• Adrenocortical adenoma
• myelolipoma
• pediatric
• myelolipomatous differentiation
• Cushing syndrome

Disclosure statement

No potential conflict of interest was reported by the authors.

Funding

There is no source of funding for the research