Sulfamic Acid Catalyzed One-Pot Synthesis of Polyhydroquinolines via the Hantzsch Four Component Condensation Reaction

Abstract

The synthesis of polyhydroquinoline derivatives has been achieved using catalytic amounts of green, inexpensive and environmentally benign sulfamic acid. The process is operationally simple and has good to excellent yields.

Keywords:

• hantzsch
• polyhydroquinoline
• solvent-free
• sulfamic acid

We gratefully acknowledge for financial support from the Research Council of Arak University.

Notes

^a Isolated yield.

^b Catalyst reused for three consecutive times.