Abstract
A one-pot multicomponent reaction of aldehydes, 2-amino benzimidazole and ethyl 2-mercaptoacetate is described as an efficient method for the synthesis of novel ethyl 2-((1H-benzo[d]imidazol-2-ylamino)(Aryl)methylthio)acetates in the presence of Ni(NO 3 ) 2 .6H 2 O as a homogeneous catalyst at room temperature. The present procedure offers several advantages, such as high yields, short reaction times and very easy workup.
We gratefully acknowledge the financial support from the Research Council of Arak University.
Notes
aIsolated yield.
bReaction was carried out under reflux conditions for 10h.
aIsolated yield.
bMelting points are not corrected.