Eco-friendly and Efficient Synthesis of Pyrano[2,3-d] pyrimidinone and Tetrahydrobenzo[b]pyran Derivatives in Water

Abstract

Tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone derivatives were synthesized efficiently in the presence of KAl(SO₄)₂.12H₂O (alum) in water. Green media, lack of toxicity, short reaction times, easy work-up and high yields are some advantages of this method.

Keywords:

• alum
• green synthesis
• heterogeneous
• water

The authors would like to acknowledge financial support from the Research Council of Arak University.

Notes

^aYields refer to isolated products.

^aYields refer to isolated products.