Abstract
A series of transition metal complexes of Zn(II), Co(II), Cu(II), Ni(II), and Mn(II) have been synthesized from Schiff's base H2Sal-2,4-toluene, [N,N′-bis(salicylidine)toluene-2,4-diamine] (IV) derived from salicylaldehyde and toluene 2,4-diamine using MORE technique. Structural features were obtained from FTIR, UV-VIS, molar conductance, ELEMENTAL analysis, 1H-NMR, mass spectral and X-ray diffraction studies, which have shown the formation of dimer complexes, where the ligand acts as a bridge between two metal cations. Ligand and complexes have been screened experimentally for their antimicrobial activity against different species of pathogenic bacteria; Viz., E. coli, S. aureus, B. subtilis and P. aureginosam and their antimicrobial potency have been discussed.
Financial support from University Grant Commission [F-33-301/2007(SR)], New Delhi is highly acknowledged. The authors are thankful to Rajiv Gandhi Biotechnology Centre, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur for conducting biological screening. Authors are thankful to VNIT, Nagpur for providing FTIR spectral analysis. The authors are grateful to IICT Hyderabad, for the help in undertaking NMR and Mass spectra.