Two Tetrachlorocuprate(II) Salts with Substituted Benzyl Pyridinium: Syntheses, Crystal Structures, and Antibacterial Properties

Abstract

Two tetrachlorocuprate(II) salts with substituted benzyl pyridinium, [BzPy]₂[CuCl₄](1) and [Bz-4-NH₂Py]₂[CuCl₄](2) ([BzPy]⁺ = 1-benzylpyridinium; [Bz-4-NH₂Py]⁺ = 1-benzyl-4′-aminopyridinium), were synthesized and characterized. The two salts comprise a [CuCl₄]^2- anion and two [BzPy]⁺ or [Bz-4-NH₂Py]⁺ cations. The [CuCl₄]^2- anion exhibits a very distorted tetrahedral and square-planar coordination geometry for 1 and 2, respectively. The C-H···Cl, N-H···Cl and C-H···Cu weak hydrogen bonds between the anion and cation found in the crystal play important roles in the stacking and stabilization of the two salts. The experimental results indicated that the two salts show good antibacterial activities for colibacillus, aurococcus, and bacillus subtilus.

Keywords:

• antibacterial activities
• crystal structure
• substituted benzyl pyridinium
• tetrachlorocuprate(II)

Acknowledgments

This work has been partially supported by the Science and Technology Project (No. 2008B080701011, No. 2010B080701002) from Guangdong Science and Technology Department and the Key Academic Program of the 3rd phase “211 Project” of South China Agricultural University (No. 2009B010100001).