Synthesis and Biochemical Activity Studies of 2,2'-[propane-1,3-diylbis(oxy)]-2,2'bis-[(benzylideneamino)benzenethiol] Ligand and Its Mononuclear Copper(II), Nickel(II), and Cobalt(II) Complexes

Abstract

A new hexadentate ligand incorporating Schiff base moities has been synthesized and its copper(II), nickel(II), and cobalt(II) complexes have been prepared and characterized by spectral methods. Elemental analyses and spectroscopic data of the Schiff base ligand and its copper(II), nickel(II), and cobalt(II) complexes are consistent with the formation of the ligand and its metal complexes. In addition to the Schiff base ligand (H₂L) and copper (II), nickel(II), and cobalt(II) complexes (5–7) were tested against the morphology of series bacteria. The copper(II), nickel(II), and cobalt(II) complexes exhibit higher activity than Schiff base ligand (H₂L) under identical experimental conditions.

Keywords:

• benzenethiol
• biological activity
• copper(II)
• cobalt(II) complex
• copper(II)
• nickel(II)

Acknowledgments

This work was supported by Karadeniz Technical University Research Fund, and its project code is 8665.