Advanced search
Publication Cover
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry Volume 43, 2013 - Issue 10
Submit an article Journal homepage
88
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Mechanistic and Kinetic Investigations on the Interaction of Model Platinum(II) Complex With Ligands of Biological Significance in Reference to the Antitumor Activity

Parnajyoti Karmakar Department of Chemistry, The University of Burdwan, Burdwan, India
,
Sumon Ray Department of Chemistry, The University of Burdwan, Burdwan, India
,
Arup Mandal Department of Chemistry, The University of Burdwan, Burdwan, India
,
Subala Mondal Department of Chemistry, The University of Burdwan, Burdwan, India
,
Subhasis Mallick Department of Chemistry, The University of Burdwan, Burdwan, India
,
Biplab K. Bera Department of Chemistry, The University of Burdwan, Burdwan, India
&
Alak K. Ghosh Department of Chemistry, The University of Burdwan, Burdwan, India
 show all
Pages 1563-1570 | Received 05 Jul 2012, Accepted 29 Dec 2012, Published online: 25 Aug 2013
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

The kinetics of interaction of cis-[Pt(cis-dach)(H2O)2]2+ (where dach is cis-1,2-diaminocyclohexane) with three different amino acids, namely L-Asparagine (L1H), L-Arginine (L2H), and L-Gluatmic acid (L3H) have been studied spectrophotometrically in the 40–60°C temperature range. The substitution was found to occur in two subsequent reaction steps: the first step is the ligand-assisted anation and the second one is the chelation step. The kinetic study has been substantiated by product isolation, IR, NMR, and ESI-MS spectroscopic analysis.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 674.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.