Synthesis, Crystal Structure, and DNA-Binding Properties of a Cadmium(II) Complex With the Bis(2-benzimidazolymethyl)amine Ligand

Abstract

A V-shaped ligand Bis(2-benzimidazolymethyl)amine (bba) and its cadmium(II) picrate (pic) complex, with composition [Cd(bba)₂](pic)₂·4DMF, have been synthesized and characterized on the basis of elemental analyses, molar conductivities, IR spectra and UV-vis measurements. In the complex, the Cd(II) ion is six-coordinated with a N₆ ligand set, resulting in a distorted octahedron coordination geometry. In addition, the DNA-binding properties of the Cd(II) complex have been investigated by electronic absorption, fluorescence and viscosity measurements. The experimental results suggest that the Cd(II) complex binds to DNA by partial intercalation binding mode.

Keywords:

• bis(2-benzimidazolymethyl)amine
• cadmium(II) complex
• crystal structure
• DNA binding property
• synthesis

Acknowledgments

The present research was supported by the National Natural Science Foundation of China (Grant No. 21367017), the Fundamental Research Funds for the Gansu Province Universities (212086), National Natural Science Foundation of Gansu Province (Grant No. 1212RJZA037), and ‘Qing Lan’ Talent Engineering Funds for Lanzhou Jiaotong University.