New Cobalt and Zinc Complexes with Schiff Base Ligands: Synthesis, Structures, and Biochemical Properties

Abstract

Two similar Schiff base ligands 2-[(2-isopropylaminoethylimino)methyl]-5-methoxyphenol (HL^a) and 2-ethoxy-6-[(2-isopropylami-noethylimino)methyl]phenol (HL^b) reacting with cobalt perchlorate and zinc iodide, respectively, in methanol gave the complexes [CoL^a₂]·ClO₄ (1) and [Zn(HL^b)₂I₂(μ-OH)]·I·MeOH (2). Both complexes were characterized by elemental analyses and IR spectroscopic method in the solid state. Single-crystal X-ray analysis was performed, which reveals that (1) is a mononuclear cobalt complex, and (2) is a dinuclear zinc complex. The Co atom in (1) is in an octahedral coordination. The Zn atoms in (2) are in tetrahedral coordination. Antibacterial activities of the Schiff base ligands and the complexes have been studied on the strains B. subtilis, E. coli, and S. aureus.

Keywords::

• Biochemical property
• cobalt complex
• crystal structure
• Schiff base
• zinc complex

Additional information

Funding

The authors are grateful to Hebei Key Laboratory of Bioinorganic Chemistry and College of Sciences of Agricultural University of Hebei for financial support.