Synthesis, X-Ray Structures, and Antimicrobial Activities of Nickel(II) and Copper(II) Complexes With Tetradentate Schiff Bases

Abstract

Two Schiff base ligands N,N′-bis(5-bromosalicylidene)-1,3-pentanediamine (H₂L¹) and N,N′-bis(2-hydroxy-1-naphthylidene)-1,3-pentanediamine (H₂L²) and their nickel(II) and copper(II) complexes [NiL¹] (1) and [CuL²] (2) have been prepared and characterized by elemental analyses, IR, and single crystal X-ray crystallographic determination. The crystal of (1) is monoclinic: space group P2₁/c, a = 9.680(2), b = 21.970(3), c = 10.728(2) Å, β = 119.550(2)°, V = 1984.8(6) ų, Z = 4. The crystal of (2) is orthorhombic: space group Pbca, a = 18.261(2), b = 12.250(1), c = 19.742(2) Å, V = 4416.2(7) ų, Z = 8. The Ni and Cu atoms in the complexes are in square planar coordination. The effect of the complexes on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans were studied.

Keywords:

• Schiff base
• nickel complex
• copper complex
• crystal structure
• antimicrobial activity

Supplementary Material

The crystallographic data of the structures described in this paper were deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CCDC-945898 for (1) and 945899 for (2). Copies of these data are available free of charge from http://www.ccdc.ac.uk/conts/retrieving.html, or from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: [phone]; or email: [email protected].

Additional information

Funding

This research was supported by the National Sciences Foundation of China (No. 20676057 and 20877036) and Top-Class Foundation of Pingdingshan University (No. 2008010).