Synthesis, Molecular Modeling, and DNA Binding of New Schiff Base Ruthenium(II) Complex and Its Catalytic Oxidation

Abstract

A new ruthenium(II) complex was derived from 4-aminoantipyrine Schiff base (L). The structural feature has been confirmed through elemental, magnetic susceptibility, and molar conductivity analysis. IR, UV-Vis, and ¹H NMR spectral studies show that the complex has composition of [Ru LCl₂] type, suggesting an octahedral geometry around the central metal ion. DNA interaction studies throw spectroscopic and viscosity measurement confirmed that complex bind through intercalative mode, which confirmed by computational data throw the calculation of thermodynamic parameter. Also, catalytic oxidation of the Ru(II) complex was carried out showing that the complex is efficient catalyst for the oxidation.

Keywords:

• ruthenium(II) complex
• catalytic oxidation
• DNA studies
• molecular modeling

Acknowledgments

The author expresses her sincere thanks to the Damietta University Faculty of Sciences, Chemistry Department, Central Lab, for helping her for carrying out her research encourage and for support.