Synthesis, Crystal Structure, and Biological Property of a Novel Tetranuclear Copper(II) Complex

Abstract

The reaction of 2-acetylpyridine, cyclopentylamine, and copper(II) bromide in methanol resulted in the tetranuclear copper(II) complex [Cu₄L₂(μ-Br)₂Br₂], where L is the dianionic form of 1-methoxy-1,3-dipyridin-2-ylpentane-1,3-diol. The complex was characterized by elemental analysis and IR spectroscopic method in the solid state. Single-crystal X-ray analysis was performed, which indicated that the complex possesses crystallographic twofold rotation axis symmetry. The complex crystallizes in the tetragonal space group P4₃2₁2 with unit cell dimensions a = b = 8.963(1) Å, c = 49.013(1) Å, V = 3937.5(8) ų, Z = 4, R₁ = 0.0665, and wR₂ = 0.1397. The outer two Cu atoms are in tetrahedrally distorted square planar geometry. The inner two Cu atoms are in distorted square pyramidal geometry. Thermal behavior and biological property on the bacteria strains B. subtilis, E. coli, and S. aureus of the complex were studied.

Keywords:

• copper complex
• tetranuclear complex
• crystal structure
• antibacterial activity

Funding

The authors are grateful to Hebei Key Laboratory of Bioinorganic Chemistry and College of Sciences of Agricultural University of Hebei for financial support.

Supplementary Material

CCDC 980235 contains the supplementary crystallographic data for the complex. The data can be obtained free of charge via http://www.ccdc.cam.ac.uk/conts/retrieving.html, or from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: [phone]; or e-mail: [email protected].