Ag Nanoparticles: An Efficient and Versatile Reagent for Synthesis of Bis(indolyl)methanes

Abstract

Ag nanoparticles are found to be an efficient catalyst for the electrophilic substitution reaction of indole with aldehydes to afford the corresponding bis(indolyl)methanes in good yields. The remarkable features of this new procedure are high conversions, shorter reaction times, cleaner reaction profiles, and simple experimental and work-up procedures.

Keywords:

• Ag nanoparticles
• aldehydes
• glyoxaldehyde
• indole
• bis(indolyl)methanes

Funding

The authors gratefully acknowledge financial support from the Research Council of Islamic Azad University of Yazd and the Islamic Azad University of Zahedan of Iran.