Efficient Synthesis of (S)-(+)-Clopidogrel Bisulfate-Capped Silver Nanoparticles

Abstract

In this work primarily one-pot synthetic development in the preparation of clopidogrel bisulfate with a polymorphic crystalline form II in 90% yield was developed. This premade antiplatelet drug has been used to protect starch-stabilized silver nanoparticles (AgNPs).

Keywords:

• (S)-(+)-clopidogrel bisulfate
• silver nanoparticles
• functionalized silver nanoparticles

Supplementary Material

Supplemental data for this article can be accessed at the publisher's website.

Funding

The authors are grateful to the Research Council of University of Guilan & Iranian Nanotechnology Initiative Council (INIC) for the financial support of this research work.