Spectral, Thermal and Biological Studies of Thiosemicarbazones of Organotin(IV) Chlorides

Abstract

New organotin(IV) complexes of the general formula R SnCl,_4-n.L [where n = 3, R = CH₃ or C₆ H₅, n = 2, R = C₆ H₅L = Schiff bases derived from the condensation of thiosemicarbazide with acetophenone (L-1), 4-nitrobenzaldehyde (L-2), glyoxal (L-3), 5-chlorosalicylaldehyde (L-4), cyclohexanone (L-5), 2-hydroxy-1-naphthaldehyde (L-6), 2-methoxybenzaldehyde (L-7), 4-methoxy-benzaldehyde (L-8), furfuraldehyde (L-9), salicylaldehyde (L-10) and benzylmethylketone (L-11)J have been synthesized and characterized by elemental analyses, conductance measurements, electronic, infra-red, far-infra-red, ¹H NMR and Sri Mössbauer spectral studies. Thermal studies of some of the complexes have been carried out using TG, DTG, DTA techniques. Mass loss considerations at main decomposition stages indicate conversion of the complexes to tin(II) sulphide. A distorted octahedral structure has been proposed for all the complexes. The complexes have also been tested against various pathogenic bacteria and fungi. A few complexes have shown considerable activity in comparison to the ligand.