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ABSTRACT
Electrospinning is a versatile technique providing highly tunable nanofibrous nonwovens. Many biomedical applications have been developed for nanofibers, among which the production of antimicrobial mats stands out. The production of scaffolds for tissue engineering, fibers for controlled drug release, or active wound dressings are active fields of research exploiting the possibilities offered by electrospun materials. The fabrication of materials for active food packaging or membranes for environmental applications is also reviewed. We attempted to give an overview of the most recent literature related with applications in which nanofibers get in contact with living cells and develop a nano-bio interface.
Abbreviations
| 3ABAPANI | = | Poly(aniline-co-3-aminobenzoic acid) |
| CA | = | Cellulose acetate |
| coPLA | = | Poly(L-lactide-co-D,L-lactide) |
| ECM | = | Extracellular matrix |
| EPS | = | Extracellular polymeric substances |
| NP | = | Nanoparticles |
| PAN | = | Polyacrylonitrile |
| PCL | = | Poly(ϵ-caprolactone) |
| PEG | = | Polyethylene glycol |
| PEO | = | Polyethylene oxide |
| PLA | = | Poly(lactic acid) or Polyester polylactide |
| PLGA | = | Poly lactic-co-glycolic acid |
| PLLCL | = | Poly(L-lactic acid) co-poly(ϵ-caprolactone) |
| PS | = | Polystyrene |
| PU | = | Polyurethane |
| PVA | = | Poly(vinyl alcohol) |
| PVP | = | Polyvinylpyrrolidone |
| β-CD | = | β-Cyclodextrin |
Funding
Financial support for this work was provided by the 291766 FP7-ERANET SUSFOOD, ERA35-CEREAL-INIA, the Spanish Ministry of Economy and Competitiveness, CTM2013-45775 and the Dirección General de Universidades e Investigación de la Comunidad de Madrid, Research Network S2013/MAE-2716. One of the authors, J.Q., thanks the University of Alcalá for the award of a pre-doctoral grant.