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Miscellany

Table of contents

Articles

1 Oxidative stress, antioxidant capacity, biomolecule damage, and inflammation symptoms of sickle cell disease in children

Sebaranjan Biswal, Huma Rizwan, Sweta Pal, Silpa Sabnam, Preetinanda Parida and Arttatrana Pal

10 The influence of MTHFR genetic polymorphisms on adverse reactions after methotrexate in patients with hematological malignancies: a meta-analysis

Pingli Yao, Xia He, Rong Zhang, Rongsheng Tong and Hongtao Xiao

20 Association of GSTT1/GSTM1 and ApoE variants with left ventricular diastolic dysfunction in thalassaemia major patients

Mable Misha Singh, Ravindra Kumar, Satyendra Tewari and Sarita Agarwal

26 A triplex probe-based TaqMan qPCR assay for Calreticulin type I and II mutation detection

Yigui Tang, Changgen Shi, Zhiyuan Wu, Ni Fan, Xiao Xu, Zhihua Kang, Xinju Zhang, Weizhe Ma and Ming Guan

32 miR-29b inhibits the progression of multiple myeloma through downregulating FOXP1

Hongyan Wang, Qiang Ding, Mingjun Wang, Mingwei Guo and Qi Zhao

39 Common themes and challenges in hemophilia care: a multinational perspective

J. Stoffman, N. G. Andersson, B. Branchford, K. Batt, R. D’Oiron, C. Escuriola Ettingshausen, D. P. Hart, V. Jiménez Yuste, K. Kavakli, M. E. Mancuso, K. Nogami, C. Ramírez and R. Wu

Case Report

49 The clinical outcomes of chronic myeloid leukemia patients harboring alternatively spliced BCR-ABL variants

Takashi Ishida, Koji Miyazaki, Sosei Okina, Tomomi Miyata, Kei Hayama, Masaaki Higashihara and Takahiro Suzuki

Articles

52 Efficacy and tolerability of rituximab and reduced-dose cyclophosphamide, doxorubicin, vincristine, and prednisolone therapy for elderly patient with diffuse large B-cell lymphoma

Kensuke Kayamori, Katsuhiro Shono, Masahiro Onoda and Akira Yokota

60 Prognostic significance of monosomal karyotype in myelodysplastic syndrome: a meta-analysis

Yi-Cun Wu, Xiao-Mei Zhang, Yuan-Dong Zhu and Wei Wu

70 Cross-sectional physician survey on the use of minimal residual disease testing in the management of pediatric and adult patients with acute lymphoblastic leukemia

Christopher Kim, Kara Delaney, Michelle McNamara, Victoria Chia and Vadim Romanov

79 Pediatric mature B-cell NHL, early referral and supportive care problems in a developing country

Felix Gaytan-Morales, Francisco Alejo-Gonzalez, Alfonso Reyes-Lopez, Miguel Palomo, Laura Rodriguez-Romo, Laura Villareal-Martínez, Adriana Sandoval-González, Aracely Lopez-Facundo, Isidoro Tejocote-Romero, Rocio Cárdenas-Cardos, Marco Aguilar-Ortiz, Farina Arreguin-Gonzalez, Eduardo Baños-Rodriguez, Deyanira Cortes-Alva, Andrea Ellis-Irigoyen, Gladys García-Becerra, Marcela Rodriguez-Campos, Pablo Gonzalez-Montalvo, Oscar Gonzalez-Ramella, Alberto Olaya-Vargas and on behalf of the Mexican Association of Pediatric Oncology and Hematology (AMOHP)

84 Comparative study of bone marrow and blood plasma levels of IL-2 in aplastic anaemia and their relationship with disease severity

Rajib De, Atreyee Dutta, Tuphan Kanti Dolai, Kakoli Ghosh and Ajanta Halder

89 The effects of storage on platelet function in different blood products

Signe Sperling, Pernille J. Vinholt, Ulrik Sprogøe, Mark H. Yazer, Henrik Frederiksen and Christian Nielsen

97 Factor VII deficiency – an enigma; clinicohematological profile in 12 cases

Preeti Tripathi, Priyanka Mishra, Ravi Ranjan, Seema Tyagi, Tulika Seth and Renu Saxena

103 Plasma fibrinogen level as possible prognostic biomarker in diffuse large B-cell lymphoma

Amira Mohamed Foad Shehata, Amira I. Aldesoky and Suzy F. Gohar

108 Relationship between genetic polymorphism of MTHFR C677T and lower extremities deep venous thrombosis

Jiasheng Xu, Kexin Li and Weimin Zhou

112 Differences in pulmonary and extra-pulmonary characteristics in severely versus non-severely fatigued recipients of allogeneic hematopoietic stem cell transplantation: a cross-sectional, comparative study

Gülşah Barğı, Meral Boşnak Güçlü and Ayhan Gülsan Türköz Sucak

123 Association of cytotoxic T-lymphocyte antigen 4 gene with immune thrombocytopenia in Chinese Han children

Liqiong Yao, Bei Liu, Li Jiang, Lanxia Zhou and Xiaoju Liu

129 ADAMTS-13 activity reduction in plasma of acute myeloid leukemia predicts poor prognosis after bone marrow transplantation

Chen Liu, Man Han, Lei Zhao, Mengjie Zhu, Qinzhu Xu, Ying Song and Hui Wang

134 Relevance of antiphospholipid antibody profile in the clinical outcome of ITP: a single-centre study

Luca Frison, Annamaria Lombardi, Ilaria Caputo, Gianpietro Semenzato, Fabrizio Fabris and Fabrizio Vianello

139 Dysfunction of immune system in the development of large granular lymphocyte leukemia

Houfang Sun, Sheng Wei and Lili Yang

148 Maternal sickle cell disease and twin pregnancy: a case series and review of the literature

Deyna Cardosa, Alexandra Ridout, Surabhi Nanda, Jo Howard, Susan E. Robinson and Eugene Oteng-Ntim

159 Risk factors for venous thromboembolism (VTE) recurrences in Thai patients without cancer

Panchalee Satpanich and Ponlapat Rojnuckarin

166 Diagnostic utility of the lymphoid screening tube supplemented with CD34 for Ogata score calculation in patients with peripheral cytopenia

Astrid Muyldermans, Lisa Florin, Helena Devos, Barbara Cauwelier and Jan Emmerechts

173 The use of octagam and gammanorm in immunodeficiency associated with hematological malignancies: a prospective study from 21 French hematology departments

Omar Benbrahim, Jean-François Viallard, Sylvain Choquet, Bruno Royer, Frédéric Bauduer, Olivier Decaux, Jean-Charles Crave, Yann Fardini, Pierre Clerson and Vincent Lévy

183 Noninvasive assessment and risk factors of liver fibrosis in patients with thalassemia major using shear wave elastography

Murtadha Al-Khabori, Shahina Daar, Said A. Al-Busafi, Humoud Al-Dhuhli, AlGhalya A. Alumairi, Moez Hassan, Sara Al-Rahbi and Umaima Al-Ajmi

189 Risk factors for hospitalizations and readmissions among individuals with sickle cell disease: results of a U.S. survey study

Robert M. Cronin, Jane S. Hankins, Jeannie Byrd, Brandi M. Pernell, Adetola Kassim, Patricia Adams-Graves, Alexis Thompson, Karen Kalinyak, Michael DeBaun and Marsha Treadwell

199 Efficacy and safety of bispecific T-cell engager (BiTE) antibody blinatumomab for the treatment of relapsed/refractory acute lymphoblastic leukemia and non-Hodgkin’s lymphoma: a systemic review and meta-analysis

Jian Yu, Wen Wang and He Huang

208 Prevalence and clinical significances of red cell alloimmunization and red cell bound immunoglobulin G in polytransfused patients with thalassemias

Anchalee Thedsawad, Orathai Taka and Wanchai Wanachiwanawin

215 Notice of Duplicate Publication

216 Association between tumor necrosis factor alpha gene polymorphisms and multiple myeloma risk: an updated meta-analysis

Yingjie Hong, Jing Yu, Gang Wang and Weisong Qiao

225 Upfront autologous hematopoietic stem cell transplantation in patients with high-risk stage III to IV Hodgkin lymphoma: a multicenter retrospective cohort study

Li Gao, Xixi Xiang, Cheng Zhang, Lei Gao, Tonghua Yang, Sanbin Wang, Bin Li, Shifeng Lou, Yi Su, Yao Liu and Xi Zhang

232 New data on FII, FV, FIX and thrombomodulin defects: blood keeps clotting in normal and in peculiar ways

Antonio Girolami, Silvia Ferrari, Bruno Girolami and Maria Luigia Randi

238 International sentinel site surveillance of patients with transfusional hemosiderosis treated with deferasirox in actual practice setting

Amal El-Beshlawy, Baba Inusa, David Beneitez Pastor, Blanca Xicoy, Maria Soledada Duran Nieto, Andreas Bruederle, Amin Azmon, Geralyn Gilotti and Mohsen Elalfy

247 Long-term safety and efficacy of deferasirox in patients with myelodysplastic syndrome, aplastic anemia and other rare anemia in Taiwan

Bor-Sheng Ko, Ming-Chih Chang, Tzeon-Jye Chiou, Te-Kau Chang, Yeu-Chin Chen, Sheng-Fung Lin, Cheng-Shyong Chang, Yin-Che Lu, Su-Peng Yeh, Tsai-Yun Chen and Wei-Shou Hwang

255 Analysis of long non-coding RNA expression in hemophilia A patients

Niloofar Naderi, Ali Namvar, Nooshin Amani, Nikoo Nasoohi and Azam Bolhassani

263 Frequency of iron deficiency anemia in pregnant and non-pregnant women suffering from restless legs syndrome

Srdjana Telarović and Lucija Čondić

268 Adjuvant radiotherapy and chemotherapy in early-stage diffuse large B cell lymphoma of head and neck with extranodal involvement

Cuiying Peng, Joshua Ho, Harrison X. Bai, Yuqian Huang, Raymond Y. Huang and Li Yang

276 Disordered bone metabolism in hereditary spherocytosis patients

Mahmut Cesur, Fatih Temiz, Can Acıpayam, Metin Kılınc and Nurten Seringec Akkececi

282 Multivariate logistic analysis of predictors of response to immunosuppressive therapy in children with aplastic anemia: a double-center study

Changjuan Gu, Xiaohua Zhu, Xiaohong Qiao, Xiaowen Zhai, Wei Shi and Xiaotian Xie

290 Therapeutic options for adult patients with previously treated immune thrombocytopenia – a systematic review and network meta-analysis

Ran Yang, Lin Lin, Hao Yao, Ou Ji and Qun Shen

300 Differentially expressed plasma proteins of β-thalassemia/hemoglobin E patients in response to curcuminoids/vitamin E antioxidant cocktails

Jirawan Panachan, Daranee Chokchaichamnankit, Churat Weeraphan, Chantragan Srisomsap, Patarabutr Masaratana, Suneerat Hatairaktham, Narumol Panichkul, Jisnuson Svasti and Ruchaneekorn W. Kalpravidh

308 Long non-coding RNAs MALAT1, MIAT and ANRIL gene expression profiles in beta-thalassemia patients: a cross-sectional analysis

Abeer Fakhr-Eldeen, Eman A. Toraih and Manal S. Fawzy

318 Denosumab effects on serum levels of the bone morphogenetic proteins antagonist noggin in patients with transfusion-dependent thalassemia and osteoporosis

Ersi Voskaridou, Ioannis Ntanasis-Stathopoulos, Dimitrios Christoulas, Linda Sonnleitner, Athanasios Papaefstathiou, Maria Dimopoulou, Albert Missbichler, Nikolaos Kanellias, Konstantina Repa, Athanasios Papatheodorou, Melpomeni Peppa, Gerhard Hawa and Evangelos Terpos

325 Correlation between RBC changes and coagulation parameters in high altitude population

Rong Zhang, Xiaochuan Yu, Yuanzhen Shen, Chunhui Yang, Fengjuan Liu, Shengliang Ye, Xi Du, Li Ma, Haijun Cao, Zongkui Wang and Changqing Li

331 GDF11 is increased in patients with aplastic anemia

Xifeng Dong, Yu Han, Iruni Roshanie Abeysekera, Zonghong Shao and Huaquan Wang

337 Minimal residual disease level predicts outcome in adults with Ph-negative B-precursor acute lymphoblastic leukemia

Nicola Gökbuget, Hervé Dombret, Sebastian Giebel, Monika Bruggemann, Michael Doubek, Robin Foà, Dieter Hoelzer, Christopher Kim, Giovanni Martinelli, Elena Parovichnikova, Alessandro Rambaldi, Josep-Maria Ribera, Marieke Schoonen, Julia M. Stieglmaier, Gerhard Zugmaier and Renato Bassan

349 Clinical variability and molecular characterization of Hbs/Gγ (Aγδβ)0-thal and Hbs/HPFH in Indian sickle cell disease patients: AIIMS experience

Hareram Pandey, Kanwaljeet Singh, Ravi Ranjan, Sanjay Kumar Pandey, Amit Sharma, Kamal Kishor, Tulika Seth, Manoranjan Mahapatra and Renu Saxena

353 Correction

354 Correction

355 Outcomes of unplanned tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: retrospective analysis of real-world experience in a single institution

Masaki Iino, Takeo Yamamoto and Yuma Sakamoto

362 Efficacy of levofloxacin as an antibacterial prophylaxis for acute leukemia patients receiving intensive chemotherapy: a systematic review and meta-analysis

Weerapat Owattanapanich and Methee Chayakulkeeree

369 Intrathecal dose intensification by CNS status at diagnosis in the treatment of children with acute lymphoblastic leukemia

Wasil Jastaniah, Naglla Elimam, Khalid Abdalla, Aeshah A. AlAzmi, Amal Algamal and Sami Felimban

378 Diagnostic and therapeutic splenectomy for splenic lymphomas: analysis of the National Cancer Data Base

Jaleh Fallah and Adam J. Olszewski

387 Serum platelet factor 4 is a promising predictor in newly diagnosed patients with multiple myeloma treated with thalidomide and VAD regimens

Ju Bai, Jianli Wang, Yun Yang, Wanggang Zhang, Fangxia Wang, Lei Zhang, Hongli Chen, Xiaman Wang, Yuandong Feng, Ying Shen, Lingjuan Huang and Aili He

392 Soluble programmed death-ligand 1 are highly expressed in peripheral T-cell lymphoma: a biomarker for prognosis

Haorui Shen, Yali Ji, Daobin Zhou, Yan Zhang, Wei Wang, Jian Sun and Wei Zhang

399 Etiology and clinico-hematological profile of pancytopenia: experience of a Mexican Tertiary Care Center and review of the literature

César Jonathan Vargas-Carretero, Omar Eduardo Fernandez-Vargas, Ana Lucía Ron-Magaña, José Alejandro Padilla-Ortega, Carlos Silvestre Ron-Guerrero and Esperanza Barrera-Chairez

405 Abnormalities of quantities and functions of CD56bright natural killer cells in non-severe aplastic Anemia

Yang Li, Shaoxue Ding, Chunyan Liu, Tong Chen, Hui Liu, Lijuan Li, Zonghong Shao and Rong Fu

413 Clinical characteristics and prognostic factors of primary extranodal classical Hodgkin lymphoma: a retrospective study

Mingzi Yang, Lingyan Ping, Weiping Liu, Yan Xie, Aliya, Yanfei Liu, Reyizha Nuersulitan, Jun Zhu, Meng Wu and Yuqin Song

Case Report

420 Compound heterozygous mutations Glu502Lys and Met527Thr of the FXII gene in a patient with factor XII deficiency

Haiyue Zhang, Siqi Liu, Chanchan Lin, Shasha Luo, Lihong Yang, Yanhui Jin, Liqing Zhu and Mingshan Wang

Articles

426 Beta-thalassemia: renal complications and mechanisms: a narrative review

Christos Demosthenous, Efthymia Vlachaki, Chrysa Apostolou, Perla Eleftheriou, Aggeliki Kotsiafti, Evangelia Vetsiou, Evdokia Mandala, Vassilios Perifanis and Pantelis Sarafidis

439 ISH Newsletter

440 Advances in the treatment and prognosis of anaplastic lymphoma kinase negative anaplastic large cell lymphoma

Xiaoli Wang, Jingjing Wu and Mingzhi Zhang

446 Clinicopathologic significance and therapeutic implication of de novo CD5+ diffuse large B-cell lymphoma

Huifen Tang, Hui Zhou, Juying Wei, Hui Liu, Wenbin Qian and Xiaohui Chen

Case Report

455 Clonal evolution in a chronic neutrophilic leukemia patient

Qi-Guo Zhang, Jing Wang, Wen-Yu Gong and Qi-Chuan Jin

Articles

459 Interactions of unstable hemoglobin Rush with thalassemia and hemoglobin E result in thalassemia intermedia

Kai Huang, Shijun Ge, Wei Yi, Hui Bi, Keqin Lin, Hao Sun, Xiaoqin Huang, Jiayou Chu, Shaohui Ma and Zhaoqing Yang

467 Time course of peripheral blood count recovery during induction chemotherapy for childhood acute lymphoblastic leukemia

Julie Dalsgaard Grunnan and Steen Rosthøj

473 The imbalance between regulatory memory B cells reveals possible pathogenesis involvement in pediatric immune thrombocytopenia

Junyue Fang, Li Lin, Dijin Lin, Ruihao Zhang, Xiuli Liu, Di Wang, Chaohui Duan and Xianghua Lin

480 Wilms’ tumor 1 mRNA expression: a good tool for differentiating between myelodysplastic syndrome and aplastic anemia in children?

Yingxi Zuo, Yifei Cheng, Leping Zhang, Yazhen Qin and Hong Luo

487 Transcriptome analysis identifies key regulators and networks in Acute myeloid leukemia

Jiaxin Ye, Daliang Luo, Jianhong Yu and Sibo Zhu

492 Clinical outcomes of immunosuppressive therapy for severe aplastic anemia patients with absolute neutrophil count of zero

Jia Liu, Xing-Yu Lu, Lang Cheng, Yan Yang, Sheng-Yun Lin, Hua Yin, Xiao-Qing Liu, Xue-Mei Wu and Guang-Sheng He

498 A systematic review and meta-analysis of the efficacy and adverse events of azacitidine-plus-lenalidomide treatment for patients with acute myeloid leukemia, myelodysplastic syndromes and chronic myelomonocytic leukemia

Chutima Kunacheewa, Pakaporn Thongthang, Patompong Ungprasert, Eakkapol Utchariyaprasit and Weerapat Owattanapanich

507 Use of decitabine for patients with refractory or relapsed acute myeloid leukemia: a systematic review and meta-analysis

Yuan-yuan Ma, Min Zhao, Yi Liu, De-feng Zhao, Li-xin Wang, Xiao-ping Chen and Li Li

516 Improvement of the hematologic toxicities of ruxolitinib in patients with MPN-associated myelofibrosis using a combination of thalidomide, stanozolol and prednisone

Minghui Duan and Daobin Zhou

521 Retracted article: Adjuvant radiotherapy in patients with diffuse large B-cell lymphoma in advanced stage (III/IV) improves the outcome in the rituximab era

Agustin Avilès, Maria-Jesus Nambo, Angel Calva, Natividad Neri, Sergio Cleto and Luis Silva

526 Statement of Retraction

527 Association of diabetes mellitus with non-Hodgkin lymphoma risk: a meta-analysis of cohort studies

Jian Xu and Tingting Wang

533 Ficolled bone marrow is superior to bone marrow buffy coat for detection of minimal residual disease in multiple myeloma

Yinlei Bai and Chor Sang Chim

538 Analysis of gene mutation characteristics in patients with chronic neutrophilic leukaemia

Bin Yin, XiuHua Chen, Feng Gao, Juan Li and Hong Wei Wang

544 Immunoglobulin D (IgD) and IgD receptor expression in diffuse large B-cell lymphoma

Xing Dai, Yu-Jing Wu, Xiao-Yi Jia, Yan Chang, Hua-Xun Wu, Chun Wang and Wei Wei

552 Minimal residual disease may be an early prognostic indicator for newly diagnosed acute myeloid leukemia patients induced by decitabine-based chemotherapy

Yehui Tan, Yu Fu, Chunshui Liu, Jingnan Sun, Shanshan Liu, Hai Lin, Qiuju Liu, Yanping Yang, Yuying Li, Long Su and Sujun Gao

559 Pathogenesis of aplastic anemia

Li Wang and Hong Liu

567 The clinical values of dysregulated DNA methylation and demethylation intermediates in acute lymphoblastic leukemia

Lin-Lin Cao, Hangqi Liu, Zhihong Yue, Lin Pei, Hui Wang and Mei Jia

577 Diagnosis and treatment of juvenile myelomonocytic leukemia

Xiong-yu Liao, Kun-yin Qiu, Jian-pei Fang, Ruo-hao Wu, Shu-yi Guo, Ke Huang and Dun-hua Zhou

Case Report

583 Targeted next-generation sequencing identified a novel ANK1 mutation associated with hereditary spherocytosis in a Chinese family

Qing Sun, Yao Xie, Penghui Wu, Shuo Li, Ying Hua, Xintian Lu and Weihong Zhao

Articles

588 Expression of BTK/p-BTK is different between CD5+ and CD5- B lymphocytes from Autoimmune Hemolytic Anemia/Evans syndromes

Ningning Duan, Manjun Zhao, Yi Wang, Yingying Qu, Hong Liu, Huaquan Wang, Limin Xing and Zonghong Shao

596 The challenges of handling deferasirox in sickle cell disease patients older than 40 years

Lorena Bedotti Ribeiro, Eliane Alves Soares, Fernando Ferreira Costa, Simone Cristina Olenscki Gilli, Sara Teresinha Olalla Saad and Bruno Deltreggia Benites

601 Expression and CpG island methylation pattern of MMP-2 and MMP-9 genes in patients with congenital factor XIII deficiency and intracranial hemorrhage

Ali Noroozi-Aghideh, Zahra Kashani khatib, Majid Naderi, Akbar Dorgalaleh, Marjan Yaghmaie, Mahdi Paryan and Shaban Alizadeh

606 Risk factors of early death in adult patients with secondary hemophagocytic lymphohistiocytosis: a single-institution study of 171 Chinese patients

Yanchun Zhao, Danlei Lu, Shanshan Ma, Li Li, Jingjing Zhu, De Zhou, Yanlong Zheng, Xiudi Yang, Lixia Zhu, Mingyu Zhu, Mixue Xie, Jianai Sun, Xiujin Ye and Wanzhuo Xie

613 Prognostic value of DNMT3A mutations in myelodysplastic syndromes: a meta-analysis

Simin Liang, Xiaojia Zhou, Hui Pan, Yichun Yang, Lin Shi and Li Wang

623 Yttrium-90 ibritumomab tiuxetan consolidation versus rituximab maintenance therapy after induction chemotherapy in patients with indolent non-Hodgkin lymphoma: a single-institution experience

Masaki Iino, Yuma Sakamoto and Tomoya Sato

631 Inhibitor eradication and bleeding management of acquired hemophilia A: a single center experience in China

Naifang Ye, Zhenzhen Liu, Guanqun Xu, Xuefeng Wang, Fang Wu, Xiaoqian Xu and Wenman Wu

637 Proteomic tools and new insights for the study of B-cell precursor acute lymphoblastic leukemia

Alí F. Citalan-Madrid, Griselda A. Cabral-Pacheco, Laura E. Martinez-de-Villarreal, Laura Villarreal-Martinez, Marisol Ibarra-Ramirez, Idalia Garza-Veloz, Edith Cardenas-Vargas, Ivan Marino-Martinez and Margarita L. Martinez-Fierro

651 Targeting on glycosylation of mutant FLT3 in acute myeloid leukemia

Xiaoli Hu and Fangyuan Chen

661 Clinical characteristics and prognostic factors in Chinese patients with classical Hodgkin’s lymphoma involving extranodal sites: a retrospective single-center study

Dong-Mei Zou, Dao-Bin Zhou, Yan Zhang, Wei Wang and Wei Zhang

669 Efficacy and safety of iron chelator for transfusion-dependent patients with myelodysplastic syndrome: a meta-analysis

JingLing Zhang, Pengchong Shi, Jin Liu, Jinggang Li and Yingping Cao

679 A systematic literature review on the use of platelet transfusions in patients with thrombocytopenia

Adrian Newland, Roy Bentley, Anna Jakubowska, Howard Liebman, Joanna Lorens, Markus Peck-Radosavljevic, Vanessa Taieb, Akiyoshi Takami, Ryosuke Tateishi and Zobair M. Younossi

720 Efficacy and safety of second-line treatment in Thai patients with primary warm-type autoimmune hemolytic anemia

Chattree Hantaweepant, Prat Pairattanakorn, Khemajira Karaketklang, Weerapat Owattanapanich and Yingyong Chinthammitr

727 The research progress of circular RNAs in hematological malignancies

Tingting Ji, Qiuni Chen, Shandong Tao, Yuye Shi, Yue Chen, Li Shen, Chunling Wang and Liang Yu

732 Routine clinical care for chronic immune thrombocytopenia purpura in Denmark, 2009–2015

Anne Gulbech Ording, Nickolaj Risbo Kristensen, Henrik Frederiksen, Naufil Alam, Shahram Bahmanyar, Waleed Ghanima, Mette Nørgaard and Christian Fynbo Christiansen

737 Re-personalization and stratification of hemophilia care in an evolving treatment landscape

Daniel P. Hart, Craig M. Kessler and Lou Aledort

742 Inflammation in deep vein thrombosis: a therapeutic target?

Delphine Borgel, Elsa Bianchini, Dominique Lasne, Tiffany Pascreau and François Saller