Solid supported synthesis of new thieno[2,3-d]pyrimidines

Abstract

A new and practical procedure for the synthesis of novel thieno[2,3-d]pyrimidines is described here. A series of thieno[2,3-d]pyrimidines was readily obtained from the corresponding aromatic and heterocyclic carboxylic acids using Montmorillonite K-10 dry media under microwave irradiation and solvent less conditions.

Keywords:

• Thiophene
• Thienopyrimidine
• Dry Media
• Solvent less
• Microwave

Acknowledgements

We express our thanks to Director of University Science Instrumentation Center, University of Delhi, Delhi for spectral analysis.