Abstract
A chemoselective, straight-forward and rapid method for oxidation coupling of thiols to the corresponding disulfides using methyltriphenylphosphonium dichromate (MTPPD) in dichloromethane at room temperature. The reaction has been carried out in excellent yield and short reaction time.
Acknowledgements
We gratefully acknowledge the funding support received for this project from the Isfahan University of Technology (IUT), I.R. Iran (A. R. H.) and Grants GM 033138, MH 065503, NS 033650 (A. E. R.) from the National Institutes of Health, USA. Further financial support from Center of Excellency in Chemistry Research (IUT) is gratefully acknowledged.