Zinc-mediated novel and efficient method for N-sulfonylation of amines in the absence of base

Abstract

A simple and efficient method of zinc dust-mediated N-sulfonylation of amines to the corresponding sulfonamides is described. The reaction is carried out under neutral and mild conditions. The significant feature of this method is the isolation of the pure product by simple work up in a short time.

Keywords:

• Sulfonyl chlorides
• Zinc dust
• Amines

Acknowledgements

N.R.R. thanks CSIR, New Delhi for the award of a fellowship.