Abstract
Different methods for the preparation of oxazolidinethiones and their more recent applications are reviewed. In this review, novel rearrangements and new reactions have also been summarized which for their homologous oxazolidinones have not been observed. The principal application of oxazolidinethiones has been as chiral auxiliaries in asymmetric aldol addition reactions for the obtention of chiral fragments containing one or two stereogenic centres with the stereochemistry required for the preparation of complex natural products.
Acknowledgements
The authors thank the VIEP (Project 47/NAT/06-G) for financial support of this research. We wish to thank Professor Horacio Olivo (from the University of Iowa) and Herbert Höpfl (from Morelos State University, UAEM) for critical reading of the manuscript. We want to give a special acknowledgement to the referee who revised the manuscript and made a great effort to improve it.