Molecular iodine as a versatile reagent for Hantzsch synthesis of 2-aminothiazole derivatives

Abstract

A simple and facile synthesis of 2-aminothiazoles has been accomplished using molecular iodine catalyzed condensation of bromoketones with thiourea. The advantage of this method is that pure products are formed very rapidly under mild conditions.

Keywords:

• 2-aminothiazoles
• molecular iodine
• bromoketones
• thiourea