Abstract
A highly efficient solvent-free and simple one-pot approach for the synthesis of 4-hydroxythiazolidine-2-thione is described. The reaction of primary amines and carbon disulfide in the presence of 2-chloroacetaldehyde afforded the title compounds in high yields.
GRAPHICAL ABSTRACT
![](/cms/asset/119afb6d-c95b-436f-9d50-cfd9dbfe2db8/gsrp_a_907407_uf0001_b.gif)
Acknowledgements
We are grateful to Dr Farzad Nikpour for his assistance.
Supplemental data
for this article can be accessed at http://dx.doi.org/10.1080/17415993.2014.907407.