Nano-CdZr₄(PO₄)₆ as a reusable and robust catalyst for the synthesis of bis-thiazolidinones by a multicomponent reaction of aldehydes, ethylenediamine and thioglycolic acid

ABSTRACT

Nano-CdZr₄(PO₄)₆ has been used as an efficient catalyst for the preparation of bis-thiazolidinones by pseudo-five-component reaction of aldehydes, ethylenediamine and thioglycolic acid under reflux conditions in toluene. The present synthetic protocol has several advantages, such as simplicity, excellent yields, short reaction times, reusability of the catalyst and low catalyst loading.

GRAPHICAL ABSTRACT

KEYWORDS:

• Bis-thiazolidinones
• nano-CdZr₄(PO₄)₆
• ethylenediamine
• catalytic activity
• one-pot reaction

Acknowledgements

Authors are grateful to Dr Shayesteh Asadollahi for his help.

Disclosure statement

No potential conflict of interest was reported by the authors.

ORCID

Javad Safaei-Ghomi http://orcid.org/0000-0002-9837-4478