An efficient synthesis of novel sulfonyl[3.3.3]heteropropellanes from sulfonylacetamidines and ninhydrin-malononitrile adduct

ABSTRACT

The synthesis in good yields of a novel class of sulfonyl[3.3.3]heteropropellanes via a one pot, five-component reaction between sodium arylsulfinates, trichloroacetonitrile, primary amines, and the malononitrile-ninhydrin adduct in H₂O at room temperature has been reported.

GRAPHICAL ABSTRACT

KEYWORDS:

• Sulfonyl[3.3.3]heteropropellanes
• ninhydrin
• malononitrile
• sodium arylsulfinates
• trichloroacetonitrile

Disclosure statement

No potential conflict of interest was reported by the authors.