Rapid and efficient deoxygenation of sulfoxides to sulfides with tantalum(V) chloride/sodium iodide system

ABSTRACT

TaCl₅/NaI system converts a wide range of sulfoxides to the corresponding sulfides in high yields with short reaction times, under mild conditions. It is worth mentioning that this protocol is chemoselective and tolerates various functional groups (such as –Br, –Cl, –OCH₃, –CHO, and –NO₂) and double bond.

GRAPHICAL ABSTRACT

KEYWORDS:

• Deoxygenation
• sulfoxide
• sulfide
• tantalum(V) chloride
• sodium iodide

Additional information

Funding

This work was financially supported by Korea University.