Abstract
The present methodology explored the effectiveness and versatility of deep eutectic solvent with ultrasonic energy as an eco-friendly protocol for the synthesis of bisthioglycolic acid derivatives. Bisthioglycolic moiety holds its role as a potent scaffold in sulfur-containing drugs. The presented strategy offers significant advantages such as green catalyst as well as solvent, excellent yield, short reaction time, and simple reaction workup. This methodology shows a wide range of substrate scope that contain both electron-donating as well as electron-withdrawing groups.
GRAPHICAL ABSTRACT
Acknowledgment
RK & JKR are thankful to SERB New Delhi for the research grant (TAR/2022/00520). PS gratefully acknowledges the National Research Foundation (SA) for a Competitive grant for rated researchers (Grant Number: SRUG2204092857). The authors are also thankful to the IKGPTU, Kapurthala for providing all the necessary research facilities.
Disclosure statement
No potential conflict of interest was reported by the author(s).