Agreement between intraoperative anterior segment spectral-domain OCT and 2 swept-source OCT biometers

ABSTRACT

Purpose: To evaluate the agreement of different biometric parameters obtained using intraoperative spectral-domain optical coherence tomography (SD-OCT) and two swept-source optical coherence tomography (SS-OCT) based biometers.

Methods: 102 eyes were assessed using the intraoperative SD-OCT integrated into the Catalys femtosecond-laser, and the IOLMaster 700 and Anterion SS-OCT-based-biometers. Central corneal thickness (CCT), anterior chamber depth (ACD), white-to-white (WTW), and lens thickness (LT) were measured.

Results: There were statistically significant differences for CCT, ACD, WTW and LT between devices (p < 0.001). The mean difference for ACD ranged from −0.067 to −0.250 mm, with the largest mean difference being between the IOLMaster 700 and Catalys. CCT mean differences ranged from 7 to 32 µm, with the largest mean difference being between the Anterion and Catalys. For WTW, the comparison between the IOLMaster 700 vs Catalys showed the largest mean difference (0.38 mm). However, the mean differences for LT from all three devices were quite similar, ranging from −0.02 to −0.08 mm.

Conclusions: SS-OCT biometers showed good agreement for ACD, CCT, WTW and LT. The SD-OCT showed ACD, CCT and WTW values that do not seem to be interchangeable with the SS-OCT biometers; however, this device did show excellent agreement in the case of LT.

KEYWORDS:

• Swept-source optical coherence tomography
• spectral domain optical coherence tomography
• optical biometer
• femtosecond laser
• anterior segment

Article highlights

• The purpose of the present study was to analyze the agreement of several parameters obtained using an intraoperative spectral-domain OCT integrated into the Catalys Precision Laser System with those obtained with two SS-OCT biometers, the IOLMaster 700 and the Anterion.

• A Bland–Altman graphical method was applied to enable pairwise comparisons with the average difference, 95% confidence interval and 95% limits of agreement.

• SS-OCT biometers showed good agreement for ACD, CCT, WTW and LT. The SD-OCT of the Catalys showed ACD, CCT and WTW values that do not seem to be interchangeable with the SS-OCT biometers; however, this device did show excellent agreement in the case of LT.

Declaration of interest

All authors report research grants from Heidelberg Engineering GmbH and Carl Zeiss Meditec AG outside the submitted work. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

Reviewer Disclosures

Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.

Additional information

Funding

This paper was not funded.