Use of Au-Zn/blood hybrid nano-fluid flow for drug delivery through the human circulatory system

Abstract

Due to their versatile characteristics in imaging, surface modification, and therapeutics, Gold and Zinc nanoparticles are widely used as nano-materials for agnostic activities. The main purpose of this research is to investigate a mathematical model of a hybrid nano-fluid passing through a porous channel having Zinc and Gold as nano-particles and blood being used as a base fluid. The present model can be very useful for effective drug delivery in blood. The main reason for using gold nanoparticles for drug delivery is because they depict promising characteristics in surface modification, therapeutics and imaging. Variable permeability of both walls allows fluid to enter and leave while a slightly differing span dilates and compresses the fluid at a consistent frequency. The provided system of governing PDEs is converted into a set of odes using the similarity transformation approach. Then, using MATLAB's built-in function bvp4c, dimensionless equations are numerically solved. Plots of the velocity and temperature profiles, along with the Nusselt numbers for the relevant parameters, are shown, and the underlying physical and logical justifications are highlighted. It has been found that the channel's asymmetry, which results from varying wall permeability has a significant impact on the nature of the fluid flow.

KEYWORDS:

• Hybrid nano-fluid
• porous walls
• squeeze flow
• drug delivery
• blood circulation
• BVP4C
• MATLAB

Acknowledgments

The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University, Abha, Saudi Arabia for funding this work through Large Groups Project under grant number RGP.2/206/43.

Disclosure statement

No potential conflict of interest was reported by the author(s).