Follow-up on: optimizing lesion detection in small bowel capsule endoscopy and beyond: from present problems to future solutions

ABSTRACT

Introduction: This review presents noteworthy advances in clinical and experimental Capsule Endoscopy (CE), focusing on the progress that has been reported over the last 5 years since our previous review on the subject.

Areas covered: This study presents the commercially available CE platforms, as well as the advances made in optimizing the diagnostic capabilities of CE. The latter includes recent concept and prototype capsule endoscopes, medical approaches to improve diagnostic yield, and progress in software for enhancing visualization, abnormality detection, and lesion localization.

Expert commentary: Currently, moving through the second decade of CE evolution, there are still several open issues and remarkable challenges to overcome.

KEYWORDS:

• Capsule endoscopy
• diagnostic yield
• detection
• small bowel
• endoscopy
• algorithm
• engineering

Declaration of interest

A. Koulaouzidis has received material research support from Intromedic. E. Toth has served as a consultant for Medtronic and Given Imaging. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

Reviewer disclosures

Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.

Additional information

Funding

This work was supported by funding from the project ‘Klearchos Koulaouzidis’, Grant No. 5151, Special Account of Research Grants of the University of Thessaly, Greece.