Utility of the Ages and Stages Questionnaires 3rd Edition for Developmental Screening in Children with Surgically Repaired Congenital Heart Disease

ABSTRACT

Aim: This study sought to evaluate the accuracy of the Ages and Stages Questionnaires 3rd Edition (ASQ-3) in identifying developmental delay (DD) in children with congenital heart disease (CHD) born at term who underwent surgical repair.

Methods: Participants had to complete ASQ-3 and Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) at 12 and 24 months. A child was considered at risk of DD for a ASQ-3 domain when he scored below the cutoff (≤-1SD or ≤-2SD). A child had a DD in a BSID-III domain when the score was ≤-1SD. The validity for each ASQ-3 domain and for overall ASQ-3 was measured.

Results: At 12 months (n = 64), overall ASQ-3 (≤-2SD) sensitivity was 88%, specificity 74%. At 24 months (n = 82), overall ASQ-3 (≤-2SD) sensitivity was 74%, specificity 88%.

Conclusion: The results support the utility of the ASQ-3 for screening the overall risk of DD in children with CHD.

KEYWORDS:

• Developmental screening
• Ages and Stages Questionnaires
• Bayler Scales of Infant and Toddler Development
• congenital heart disease

Acknowledgments

We are grateful to the families who participated in our study. We give particular credit to Lionel Carmant, MD, for his implication in co-founding the CINC and for his contribution throughout every step of this study including the funding process.

Disclosure statement

All authors have no potential conflicts of interest to disclose.

Additional information

Funding

This work was supported by a scholarship awarded to Mr Lépine by the Programme d’Excellence en Médecine pour l’Initiation En Recherche of the Faculty of medicine of the Université de Montréal and by the Heart and Stroke Foundation of Canada under grant number G-16-00012606 held by Anne Gallagher