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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 75, 2020 - Issue 4
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Case Report

A rare case of hemodialysis-related portosystemic encephalopathy and review of the literature.

Barbara Geerinckxa Department of Nephrology, University Hospital of Antwerp, Edegem, Belgium;b Department of Gastro-enterology and Hepatology, University Hospital of Antwerp, Edegem, BelgiumCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7687-2273
ORCID Icon,
Rachel Hellemansa Department of Nephrology, University Hospital of Antwerp, Edegem, Belgium
,
Amaryllis H. Van Craenenbroecka Department of Nephrology, University Hospital of Antwerp, Edegem, Belgium;c Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Edegem, Belgium
,
Sven Francqueb Department of Gastro-enterology and Hepatology, University Hospital of Antwerp, Edegem, Belgium
,
Liesbeth De Waelea Department of Nephrology, University Hospital of Antwerp, Edegem, Belgium
,
Jeroen Kerstens
ORCID Icon,
Pieter-Jan Van Gaala Department of Nephrology, University Hospital of Antwerp, Edegem, Belgium
,
Bart Bracked Department of Hepatobiliary Surgery, University Hospital of Antwerp, Edegem, Belgium
,
Peter Michielsenb Department of Gastro-enterology and Hepatology, University Hospital of Antwerp, Edegem, Belgium
&
Thomas Vanwolleghemb Department of Gastro-enterology and Hepatology, University Hospital of Antwerp, Edegem, BelgiumORCID Iconhttps://orcid.org/0000-0002-0572-8741
ORCID Icon show all
Pages 296-300 | Published online: 28 Mar 2019
 
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ABSTRACT

Hemodialysis-related portosystemic encephalopathy (HRPSE) is a clinical phenomenon where portosystemic encephalopathy (PSE) develops without liver dysfunction, usually caused by changes in the portosystemic blood flow related to hemodialysis. We describe the case of a 22-year old patient with a transjugular intrahepatic portosystemic shunt (TIPS) who developed HRPSE several months after initiation of hemodialysis. Despite initial therapy with laxatives and neomycin symptoms recurred. It was only after relocation of the hemodialysis catheter from the superior caval vein to the femoral vein that symptoms completely resolved.

Disclosure statement

No potential conflict of interest was reported by the authors.

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