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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 76, 2021 - Issue 2
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Case Report

Diabetes insipidus and acute myeloid leukemia harboring monosomy 7: report of two cases and literature review

Huu Hanh Lêa Medical School, University of Liège, Liège, Belgium;b Department of Nephrology, Grand Hôpital de Charleroi, Gilly, Belgium;c Department of Hematology, Grand Hôpital de Charleroi, Gilly, Belgium
,
Jean-Philippe Lengeléb Department of Nephrology, Grand Hôpital de Charleroi, Gilly, BelgiumCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0134-1769
ORCID Icon,
Marie Henind Department of Radiology, Grand Hôpital de Charleroi, Gilly, Belgium
,
Sébastien Toffolie Centre for Human Genetics, Institute of Pathology and Genetics, Gosselies, Belgium.
&
Philippe Mineurc Department of Hematology, Grand Hôpital de Charleroi, Gilly, Belgium
Pages 132-135 | Published online: 27 Aug 2019
 
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ABSTRACT

Acute myeloid leukemia (AML) is unusually associated with diabetes insipidus (DI) in patients bearing monosomy 7 or chromosome 3 aberrations. To date, 84 cases have been reported worldwide. Physiopathological mechanisms linking these chromosomal abnormalities to DI are not yet understood. We report two patients with AML/DI and review the medical literature on those conditions.

Disclosure statement

No potential conflict of interest was reported by the authors.

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