ABSTRACT
Tolerance to combined kidney and hematopoietic cell transplant has been achieved in humans after establishment of mixed chimerism allowing for the withdrawal of immunosuppressive drugs. The seminal contributions of Ray Owen provided the scientific basis for the human protocol.
Disclosure of potential conflicts of interest
No potential conflicts of interest were disclosed.
Funding
Research on clinical tolerance at Stanford was supported by a grant (5 PO1 HL075462) from the National Heart, Lung and Blood Institute.