ABSTRACT
Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this study, we examined their antifungal activity against C. albicans in vitro. Among the alkaloids studied in this work, berberine hydrochloride showed the best activity against C. albicans.
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Notes on contributors
Juliana Noguti
Juliana Noguti, DDS, MS, PhD, is a research associate in the division of periodontology, diagnostic sciences and dental hygiene at the Herman Ostrow School of Dentistry of USC.
Conflict of Interest Disclosure: None reported.
Mersedeh Rajinia
Mersedeh Rajinia is an undergraduate student in the division of periodontology, diagnostic sciences and dental hygiene at the Herman Ostrow School of Dentistry of USC.
Conflict of Interest Disclosure: None reported.
Bruna Raquel Zancope
Bruna Raquel Zancope, DDS, MS, is a doctoral student and visiting scholar from the State University of Campinas, Piracicaba Dental School, department of pediatric dentistry, in São Paulo, Brazil.
Conflict of Interest Disclosure: None reported.
Maria Carolina Salome Marquezin
Maria Carolina Salome Marquezin, DDS, MS, is a doctoral student and visiting scholar from the State University of Campinas, Piracicaba Dental School, department of pediatric dentistry, in São Paulo, Brazil.
Conflict of Interest Disclosure: None reported.
Dalia Seleem
Dalia Seleem, DDS, is a doctoral candidate in the division of periodontology, diagnostic sciences and dental hygiene at the Herman Ostrow School of Dentistry of USC.
Conflict of Interest Disclosure: None reported.
Vanessa Pardi
Vanessa Pardi, DDS, MS, PhD, is an assistant professor of dentistry in the division of periodontology, diagnostic sciences and dental hygiene at the Herman Ostrow School of Dentistry of USC.
Conflict of Interest Disclosure: None reported.
Ramiro M. Murata
Ramiro M. Murata, DDS, MS, PhD, is an assistant professor of dentistry in the division of periodontology, diagnostic sciences and dental hygiene and biomedical sciences at the Herman Ostrow School of Dentistry of USC.
Conflict of Interest Disclosure: None reported.