Risk assessment of patulin intake through apple-based food by infants and preschool children in Serbia

ABSTRACT

This study reports for the first time in Serbia the occurrence of patulin in apple-based food and the risk assessment associated with patulin intake by infants and preschool children. In total, 214 samples of infant fruit juices (48), infant purée (66), and juices for children (small package with straw, 100) were collected over 3 years (2013–15) and analysed using HPLC with ultraviolet detection. Patulin was found in 43.8% of infant juices and 16.7% of infant purée, with all values below the legal limit of 10 μg kg⁻¹ (maximum 8.3 and 7.7 μg kg⁻¹, respectively). The proportion of contaminated samples among fruit juices for children was 43.0%, with the highest patulin concentration at 30.2 μg kg⁻¹, not exceeding the maximum allowed level of 50 μg kg⁻¹. Risk assessment of patulin intake by Serbian infants and preschool children, conducted by deterministic and probabilistic approaches, revealed a hazard quotient well below 1, indicating a tolerable exposure level and no health concern.

KEYWORDS:

• Patulin
• apple
• infants
• children
• risk assessment

Acknowledgments

This research was performed under financial support to CESAM by the Portuguese Foundation for Science and Technology (FCT) (UID/AMB/50017/2013), through national funds, and the co-funding by the FEDER (POCI-01-0145-FEDER-00763), within the PT2020 Partnership Agreement and Compete 2020.

Conflict of interest

The authors declare that there are no conflicts of interest.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the FEDER [POCI-01-0145-FEDER-00763]; Portuguese Foundation for Science and Technology (FCT) [UID/AMB/50017/2013].