Dissipation and residue of triadimefon in Rosa roxburghii

Abstract

Rosa roxburghii (R. roxburghii) is a unique, edible, medicinal fruit rich in vitamin C found in Southwest China. Triadimefon (TDF) is a triazole fungicide that is widely used to control powdery mildew in R. roxburghii. To assess the safety of TDF in R. roxburghii, an LC-MS/MS method was developed for the simultaneous quantification of TDF and its major metabolite, triadimenol (TDN) in R. roxburghii. Both TDF and TDN showed high correlation coefficients (>0.999) for the solvent- and matrix-matched calibrations. The recovery rates of TDF and TDN in R. roxburghii ranged from 90.18% to 100.42%, with a relative standard deviation (RSD) of 1.25%–9.22%. The limit of quantification (LOQ) was 0.01 mg·kg⁻¹. The half-life of TDF in R. roxburghii was between 2.74 and 3.07 days, with terminal residues ranging from < LOQ to 1.84 mg·kg⁻¹. Recommended maximum residue limits (MRLs) and safe pre-harvest intervals (PHIs) for TDF in R. roxburghii were 0.5 mg·kg⁻¹ and 21 days, respectively. This study provides essential data for TDF’s safe and judicious use in R. roxburghii production.

Keywords:

• Triadimefon
• triadimenol
• Rosa roxburghii
• dissipation
• residue

Acknowledgments

Authors gratefully acknowledge the financial support from the National Natural Science Foundation of China (No. 32160656), Guizhou Provincial Innovation Talent Team (No. CXTD [2023]015), the Science-Technology Support Program of Guizhou Province (No. [2021]YB243), and the Hundred Level Talent Foundation of Guizhou Province (No. GCC [2022]023-1).

Data availability statement

The authors confirm that all data generated or analyzed during this study are available within the article.