Nanofiber membranes from cellulose triacetate for chiral separation

ABSTRACT

Nanofiber membranes and molecularly imprinted nanofiber membranes were prepared from cellulose triacetate (CTA) by electrospray deposition. CTA nanofiber membrane incorporated L-Glu in preference to D-Glu from racemic mixture of Glu. Z-L-Glu molecularly imprinted nanofiber membranes showed adsorption selectivity toward the enantiomer, of which absolute configuration was same as that of the print molecule. Adsorption isotherms revealed that specific adsorption sites toward L-Glu were found in the control CTA nanofiber membrane and the Z-L-Glu molecularly imprinted CTA one (CTA-L). The affinity constant between L-Glu and specific adsorption site in the control CTA nanofiber membrane was determined to be 3.8 × 10³mol⁻¹dm³ and that for CTA-L one to be 7.9 × 10³mol⁻¹dm³, respectively. The control CTA nanofiber membrane selectively transported D-Glu. The permselectivity for the CTA nanofiber membrane was determined to be 1.47. Those nanofiber membranes gave high flux values, and the molar mobility for those was over 1.0 × 10⁻⁸mol cm cm²J⁻¹h⁻¹.

Keywords:

• Cellulose triacetate
• Chiral separation
• Electrospray deposition
• Isotherm
• Nanofiber membrane
• Optical resolution
• Permslectivity

Notes

7th Aseanian Membrane Society Conference (AMS7), 4–7 July 2012, Busan, Korea