Early detection onset of flap failure using near infrared spectroscopy

Abstract

Background

Near-infrared spectroscopy (NIRS) is widely used to assess flap perfusions by measuring tissue oxygen saturation (StO₂). However, the StO₂ level for the onset of perfusion failure is still a controversial issue.

Aim

This study proposes a new threshold of StO₂ level for detecting the onset of perfusion failure as early as possible to increase flap salvage rates.

Methods

Twenty patients undergoing flap surgery were included in this study – 13 flaps were implemented to cover defects that occurred due to trauma and 7 flaps to hide imperfections that occurred after cancer treatment. Thirteen flaps were in the lower extremity, six in the mandible, and one in the breast. NIRS was used to measure StO₂ in 240 flap regions of the 20 patients to determine flap viability using descriptive statistics.

Results

The mean StO₂ values from healthy flap and control regions were obtained as 81.6% ± 0.36 and 82% ± 0.18, respectively. The lowest StO₂ value of 77.2% was defined as the onset of a vascular complication at a probability of 99.74% by subtracting three times the standard deviation from the mean StO₂ of healthy flaps. Vascular complications were observed from 21 regions in the four flaps with StO₂ values lower than 77.2%, but only one was lost.

Conclusion

The threshold value for the onset of perfusion failure was a 5% decrease from the expected value, much lower than previously described thresholds that may facilitate the detection of perfusion failure in the early stage and increase salvage rates in flap revisions.

Keywords:

• Detection of the onset of flap failure
• perfusion failure
• near-infrared spectroscopy
• tissue oxygen saturation

Disclosure statement

No potential conflict of interest was reported by the authors.

Grant information

The study was approved by the Akdeniz University Institutional Review Board (24.03.2013/122). All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008. Informed consent was obtained from all patients for being included in the study