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Research

An appraisal of blood pressure control and its determinants among patients with primary hypertension seen in a primary care setting in Western Nigeria

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Pages 192-201 | Received 16 Mar 2016, Accepted 25 Apr 2016, Published online: 29 Jun 2016

Abstract

Background: Achieving guideline-recommended blood pressure is imperative in reducing the rising tide of uncontrolled hypertension and its attendant sequelae, which are major causes of morbidity and mortality globally. The aim of the study was to describe the pattern of blood pressure control and identify the factors influencing blood pressure control among patients with primary hypertension seen at family medicine clinics of FMC, Abeokuta.

Methods: This was a descriptive cross-sectional hospital-based study. A systematic random sampling technique was used in selecting 360 hypertensive respondents over four months. Data were collected through a pre-tested interviewer-administered questionnaire. The Statistical Package for the Social Sciences (SPSS) version 17.0 was used to analyse data.

Results: Blood pressure was controlled in 167 (46.4%) of the respondents. The independent predictors of blood pressure control were female gender (p = 0.001, OR = 2.494, 95% confidence interval (CI) = 1.477–4.214), regular use of medication (p = 0.001, OR = 2.900, 95% CI = 1.508–5.577), regular clinic attendance (p < 0.001, OR = 3.512, 95% CI = 1.772–6.960), and absence of diabetes mellitus (p < 0.001, OR = 7.357, 95% CI = 3.190–16.966).

Conclusions: The rate of blood pressure control among the hypertensive respondents was low. Multiple independent predictors of controlled blood pressure call for a team-based approach as well as multiple approaches including education of patients, expansion of a community-based health insurance programme and intensification of treatment efforts when managing hypertensive patients.

Introduction

Hypertension is a major public health problem globally with a greater population burden in developing than developed countries.Citation1,2 In developed countries, only 7% of deaths under the age of 60 are caused by uncontrolled hypertension and its complications, while this increases to 25% in the African region.Citation3 In a multi-centre study of cardiovascular diseases in Nigeria, hypertension ranked first and its complications constituted 25% of medical admissions in urban hospitals in the country.Citation4

The goal of therapy is to normalise blood pressure (BP) and prevent cardiovascular events. However, in clinical practice, recommended BP is sometimes difficult to achieve.Citation1,5 An Internet search on analysis of BP control showed poor control rates in most countries with the highest rate of 51.8% noted in Hong Kong.Citation5 The growing problem of inadequate BP control is not different in Nigeria. Poor BP control of less than 50% is consistent in most studies.Citation6–8 Therefore, understanding the factors associated with uncontrolled hypertension could help improve patients’ care by finding an effective way of addressing these barriers, and hence reduce the burden on the health facility, family and individual.

Most tertiary health centre based studies on BP control in Nigeria were carried out in the cardiology clinic.Citation6–9 The few tertiary health centre based studies done in the family medicine clinic recruited patients only from the General Outpatient Clinic (GOPC).Citation10,11 With the advent of the National Health Insurance Scheme (NHIS) in Nigeria, most family medicine departments in our tertiary hospital attend to NHIS patients at the NHIS clinic. There is no tertiary health centre based study done in the family medicine department on BP control that recruited NHIS patients. It is against this background that the researchers were motivated to study BP control and its determinants among adults with primary hypertension in a family medicine clinic comprising of out-of-pocket patients and insurance patients (NHIS).

Subjects and methods

Study setting

Abeokuta is the capital of Ogun state in South West Nigeria. As of 2005, Abeokuta and the surrounding area had a population of 593,140.Citation12 The city is known for its traditional style of hand-woven cotton cloth known as ‘adire’, which is dyed with locally produced indigo. The Federal Medical Centre, Abeokuta is a tertiary institution with a tripartite mandate of training and research, and service delivery. It also serves as a referral centre for primary and secondary public health institutions as well as missionary and private hospitals in Ogun state, and neighbouring south-western states of Nigeria. The family medicine clinics comprising the general outpatient clinic (GOPC), corporate clinic (COOP) and National Health Insurance Scheme clinic (NHIS) are the primary care clinics of the hospital. Patients that are seen at the GOPC buy their drugs out of pocket. Members of staff of the hospital and well-to-do members of the public are seen at the COOP clinic. All members of staff seen at the COOP clinic are enrolled under the NHIS while the members of the public seen at the COOP clinic buy their drugs out of pocket. Members of the public who enrolled under the NHIS are seen at the NHIS clinic. The clinics are run by consultant family physicians and postgraduate resident doctors in family medicine.

Study design

This study was a hospital-based, cross-sectional descriptive study conducted on 360 adults aged 18 and above with primary hypertension who attended the GOPC, COOP and NHIS clinics of FMC, Abeokuta between May and July 2013. The estimated population per year based on the number of adult patients with essential hypertension (cases) that attended the three clinics in 2011 was 2982. The GOPC, NHIS and COOP clinics had 1502 (50.4%), 836 (28.0%) and 644 (21.6%) attendees respectively.

Inclusion criteria

(1)

Patients aged 18 years and above with essential hypertension.

(2)

Patients with essential hypertension who had been on outpatient treatment for hypertension in the clinic for at least one year.

Exclusion criteria

(1)

Patients with secondary hypertension.

(2)

Patients with major psychiatric illness.

(3)

Patients with a severe illness that makes it difficult to follow the study protocol.

Sample size determination

The sample size (n) was calculated using the formulaCitation13 n = z2pq/d2. At 95% confidence interval and a precision level of 5%, z = 1.96 and d = 0.05. The proportion of hypertensive patients with controlled blood pressure (p) was 39% from previous study.Citation14 Therefore, p = 0.39 and q = 1 – 0.39 = 0.61. Then, (n) = 1.962x0.39x0.61/0.052 = 365.6.

Since the number of patients with essential hypertension (N) that attended the three clinics in 2011 was 2982 (less than 10,000), the sample size was adjusted by the formulaCitation13 nfn/ (1+n/N). Thus, nf = 365.6/ (1+365.6/2,982) = 325.7, which is approximately 326.

The minimum sample size was 326. However, 10% of the total sample size was added to the minimum sample size to improve the power of the study. This gave a sample size of 360 respondents.

Sampling technique

Proportionate sampling was predetermined for each clinic (180 for GOPC, 100 for NHIS and 80 for COOP) representing 50.4%, 28.0% and 21.6% respectively of 360 (the sample size). A systematic random sampling technique was utilised to select 360 hypertensive patients from the three clinics. The total number of adult patients with essential hypertension that attended the three clinics in 2011 was 2982. This translated to 960 estimated respondents in four months of data collection. The sampling interval ‘k’ was calculated thus; kN/n where ‘n’ is the sample size (360), and ‘N’ is the estimated population size within the study period (960) K = 960/3602.67 ≈ 3. The first person was selected from the first three patients with essential hypertension arriving at each clinic by simple random sampling (balloting) once at the outset of the study. Thereafter, every consenting third person was recruited until the required number (180 for the GOPC, 100 for the NHIS clinic and 80 for the COOP clinic) was achieved.

Data collection tool and process

Eligibility for the study was determined and consent (Appendix I) was taken. Data were collected by the principal investigator and two trained research assistants (resident doctors in the Department of Family Medicine, FMC, Abeokuta) through interview using a pretested questionnaire (Appendix II). The pretesting of the questionnaire was conducted on 25 hypertensive patients who were selected haphazardly from the GOPC of Sacred Heart Hospital, Lantoro and it lasted for 2 days. The pretesting was done to find out how the questionnaire would interact with the respondents and ensured that there were no ambiguities. Necessary adjustment was made after the pretest.

The pretested questionnaire Appendix II consisted of four sections: socio-demographic variables, social history, clinical factors and physical examination. It extracted information regarding patients’ demographic factors, level of education, average monthly earnings, family history of hypertension, clinic attendance, self-reported use of antihypertensive medications, practice of exercise, co-morbid conditions like asthma and diabetes mellitus and patients’ knowledge about hypertension.

To assess respondents’ knowledge about hypertension, participants’ idea of hypertension, its cause, duration of treatment, what blood pressure control entails and the consequences of lack of consistent blood pressure control were assessed. There were 11 questions on patients’ knowledge about hypertension in the predesigned questionnaire. Adequate response to each question was scored as 1. A total score of greater than or equal to 7 was considered to be good knowledge of hypertension while a score of ≤ 6 was considered poor knowledge.

Assessment of practice of exercise was self-reported. Participants were considered to engage in exercise if he or she said yes to the question ‘Do you exercise?’. Practice of exercise was regarded to be adequate if the respondent engaged in exercise at the recommended frequency (at least 3 times in a week and for more than 30 minutes during each session). Adherence to medication was obtained from each respondent through self-report. It was regarded as ‘regular’ if the respondent said yes to the question ‘Do you take your drugs regularly?’. Adherence to clinic attendance was regarded as ‘poor’ if respondents had failed to keep a clinic appointment at least once in the previous six months. Participants were regarded as having diabetes mellitus if they had been diagnosed previously by a doctor or if they were receiving insulin or oral antidiabetic medications.

Blood pressure measurement for each subject was taken in the clinic using an Accosson® mercury sphygmomanometer (AC Cossor & Son (Surgical) Ltd. London, England) after subjects had rested for five minutes. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured at Korotkoff phases I and V respectively.Citation15 The average of two blood pressures taken in the sitting position at intervals of two minutes was added to two previous blood pressure readings in the last two visits within the last six months from the patients’ record. The average of the three blood pressure readings was used as an indication of level of control.Citation16 Blood pressure greater than or equal to 140/90 mmHg in non-diabetics and greater than or equal to 130/80 mmHg in diabetics was classified as uncontrolled.Citation17

The waist circumference was measured with a tape measure as the horizontal circumference midway between the lowest rib and the iliac crest at the end of a normal expiration. The measurement was repeated twice and the average of the two measurements obtained was calculated if they were within one centimetre of one another. When the difference between the two measurements exceeded 1 cm, the two measurements were repeated. A waist circumference of more than 40 inches (102 cm) in men and greater than 35 inches (88 cm) for women was considered abnormal.Citation18

Statistical analysis

Data were entered into the Statistical Package for Social Sciences® (SPSS Inc., Chicago, USA) version 17.0 program. Continuous variables were summarized as mean and standard deviation while categorical variables were summarised as percentages. BP control was the main outcome (dependent) variable, while socio-demographic characteristics and clinical factors were the independent variables. A chi-square test was used to determine the association between BP control and the various independent variables. The level of significance was set at a p-value of less than or equal to 0.05 and a confidence interval (CI) of 95%. Logistic regression analysis was used to identify the independent predictors of BP control. The odds ratios (OR) and 95% confidence intervals (95% CI) for the predictor variables were then calculated.

Ethical consideration

Ethical approval was obtained from the Ethics Committee of the hospital. Informed consent was also obtained from the respondents included in the study.

Results

A total of 360 randomly selected hypertensive patients were studied. The age range of the respondents was 35–84 years. They were mainly in the middle age group (n = 220 [61.1%]) with a mean age of 55.4 ± 10.5. There were more female (n = 214 [59.4%]) than male (n = 146 [40.6%]) respondents with a male-to-female ratio of 1:1.5.

Two hundred and sixteen (n = 216 [60%]) respondents reported that they took their drugs regularly. The percentage of respondents that reported regular use of their antihypertensive medications in the GOPC, COOP and NHIS clinics were 50%, 68.8% and 71.0% respectively. The proportion of respondents that attested to practising any form of exercise was 36.9% (133) and less than half of them exercised at the recommended frequency (at least 3 times in a week and for more than 30 minutes per session). Among the studied participants, 49 (13.6%) respondents had co-morbid diabetes mellitus. Only one-third of the respondents (n = 120 [33.3%]) had health insurance.

Using the average BP as explained in the methodology, the mean systolic BP (SBP) in the study population was 138.8 ± 17.2 mmHg while mean diastolic BP (DBP) was 84.1 ± 9.7 mmHg. One hundred and sixty-seven (46.4%) respondents achieved target BP (BP < 140/90 mmHg in non-diabetics and BP < 130/80 mmHg in diabetics) while this was not achieved in 193 (53.6%) respondents (Figure ).

Figure 1: Pattern of blood pressure control among respondents.

Figure 1: Pattern of blood pressure control among respondents.

The number of the respondents who achieved control (SBP and DBP within normal range) in the GOPC, NHIS and COOP clinics was 69 (38.3%), 53 (53.0%) and 45 (56.3%) respectively (Table ).

Table 1: Comparison of blood pressure control in the three clinics

There was a significant association between BP control and gender (χ2 = 5.332, p = 0.021), self-report on use of medication (χ2 = 56.361, p < 0.001), clinic attendance (χ2 = 57.741, p < 0.001), diabetes mellitus (χ2 = 17.908, p< 0.001) and type of clinic attended by respondents (χ2 = 9.582, p = 0.008) (Tables and ).

Table 2: Relationship between blood pressure control and socio-demographic factors

Table 3: Relationship between blood pressure control and clinical factors

The independent predictors of controlled BP after logistic regression analysis were female gender (p = 0.001, OR = 2.49, 95% CI = 1.48–4.21), regular use of medications (p = 0.001, OR = 2.90, 95% CI = 1.51–5.58), regular clinic attendance (p < 0.001, OR = 3.51, 95% CI = 1.77–6.96), and absence of diabetes mellitus (p < 0.001, OR = 7.36, 95% CI = 3.19–16.97) (Table ).

Table 4: Logistic regression analysis of significant factors associated with blood pressure control

Discussion

The BP control rate of 46.4% is high when compared with the rates reported in various Nigerian studies.Citation6,8,19 Suboptimal control rates of 36% in Ibadan, South West Nigeria,Citation19 24.2% in Portharcourt, South South NigeriaCitation6 and 12.4% in Zaria, Northern NigeriaCitation8 have been reported. All studies mentioned above recruited respondents from the cardiology clinic. The observed difference could be attributed to the fact that patients with complicated and secondary hypertension who are likely to have difficult BP control are likely to be seen in this clinic when compared with primary care clinic. A study in Ilorin, South West NigeriaCitation,7 however, reported a higher control rate of 53.3%. The higher BP control rate in the later study might be due to the different definition of controlled BP in this index study and the Ilorin study. The use of the higher BP cut-off of 140/90 mmHg for controlled blood pressure among hypertensive-diabetics in the Ilorin study may explain this difference.

The BP control rate among patients recruited from the GOPC was low (38.3%) when compared with the NHIS clinic (53.0%) and COOP clinic (56.3%). The reasons for this may be due to the highly subsidised drugs that NHIS clinic and some COOP clinic respondents get through health insurance. Second, hypertensive members of staff of the hospital, who are expected to be health conscious, are seen at the COOP clinic. Lastly, patients recruited from the NHIS and COOP clinics had better medication adherence than GOPC patients in this study. Hypertensive patients with access to health insurance had been shown to have better medication adherence and BP control.Citation20,21

A control rate of 53% among respondents recruited from the NHIS is still inadequate considering the fact that respondents from this clinic had access to highly subsidised medications. This finding of suboptimal control rate in spite of highly subsidised drugs is in consonance with finding from a previous Nigerian studyCitation,19 which also showed poor control rate (36%) among hypertensive patients studied despite availability of free drugs. This implies that factors other than poverty might be much important in BP control. Physicians who manage hypertension should pay attention to adequate dosing, appropriate drug combinations and patients’ adherence to therapeutic plans.

Female respondents were 2.5 times more likely to have their BP controlled than male respondents (p = 0.001, OR = 2.494, 95% CI = 1.477–4.214). This is in keeping with the reports from previous studies where BP control has been shown to be better in female respondents.Citation19,22,23 This is perhaps because women are more likely to get treated and adhere to therapeutic plans than men.Citation24,25

Respondents who used their medications regularly had approximately threefold higher odds of having their BP controlled (p = 0.001, OR = 2.900, 95% CI = 1.508–5.577). This result supports the existing body of knowledge that regular use of antihypertensive medications positively impacts on BP control.Citation10,26 Of interest, one Nigerian study that excluded hypertensive patients with poor drug compliance still reported a BP control rate of 24.2%.Citation6 This may suggests that adherence to medications, though important, cannot be a lone factor. It is thus necessary to consider patient, physician and health facility related barriers to optimal BP control when managing these patients.

Hypertensive respondents who attended for follow-up regularly had a 3.5-fold higher odds of having their BP controlled (p < 0.001, OR = 3.512, CI = 1.772–6.960). This association is expected since clinic attendance ensures regular BP check and aggressive treatment by the managing physician in cases of uncontrolled BP. Owing to the asymptomatic nature of hypertension, patients tend to use the same anti-hypertensive drug prescribed earlier by the physician even in the face of poorly controlled BP. Regular clinic attendance detects uncontrolled BP and ensures appropriate management by the attending physician.

Absence of diabetes mellitus was also shown to be an independent predictor of controlled BP. This finding is similar to reports from other parts of Nigeria.Citation7,9,27 A German study also reported that having diabetes mellitus was a negative determinant of controlled BP.Citation23 Plausible reasons for this poor control rate in hypertensive patients with co-morbid diabetes mellitus might be due to microvascular and macrovascular complications seen in diabetes mellitus. The pill burden in such patients who require more drugs than patients who had only hypertension may be too much for these patients to follow especially if they have poor coping ability as a result of their disease. The high cost of multiple drugs is an additional burden, especially on the economically deprived patient.

The finding of 18.4% control rate among participants who had diabetes mellitus in this study is low when compared with the 23.7%Citation7 reported in Ilorin, Nigeria. A BP control target of ≤ 140/90 mmHg used for diabetes mellitus patients in the later study might have contributed to the higher control rate documented. Studies using a BP goal of < 140/90 mmHg in hypertensive people with diabetes mellitus might overestimate BP control rates.Citation28,29 This study confirmed that achieving optimal BP control in hypertensive patients with co-morbid diabetes mellitus is often challenging and difficult as only a minority of patients with diabetes mellitus had their BP below the recommended goal. This observation reinforces the need for intensive BP control in diabetics.

The proportion of respondents who were enrolled in health insurance with controlled BP was greater compared with those who were not enrolled (51.7% versus 43.8%). A surprising finding in this study is the fact that enrolment in the National Health Insurance Scheme was not statistically significantly associated with BP control. While this agrees with the study by Hyman et al.Citation30 in the United States of America, which also found no association between BP control and health insurance, it is at variance with many studies that have consistently established a significant association between controlled BP and possession of health insurance.Citation21,22

Perhaps the failure of this study to find an association between BP control and health insurance might be as a result of the relatively small number of respondents with health insurance in the study population and consequently insufficient statistical power to detect a difference. Poor quality of health care from other factors such as physician inertia may also be responsible. The implication of the finding is that availability of highly subsidised drugs alone may not be enough to ensure compliance and improve control. Therefore, holistic care taking into cognisance patient-related factors, physician-related factors and support from the family is essential in hypertension management.

This study showed that patients’ knowledge about hypertension did not seem to have a significant effect on BP control (p = 0.093). Likewise, a Sudanese study Citation31 showed that good patients’ knowledge regarding the complications of hypertension did not correlate positively with BP control. This is not unexpected, as good knowledge may not translate to the right attitude and practice. Contrary to this study, other researchers have shown that patients’ knowledge about hypertension was significantly related to the rate of BP control.Citation32,33 The observed difference may be due to lack of a uniform standardised tool in assessing knowledge in patients with hypertension.

The failure of this study to find an association between BP control and the practice of exercise may be attributed to the fact that it might be a lot more difficult to see the effect of prevention than to see the effect of intervention as what respondents reported as adequate exercise may be inadequate. It is, however, worthy of mention that despite the fact that the practice of any form of exercise was self-reported, the proportion of respondents who practised any form of exercise was still small (36.9%). Even among those who did practise any form of exercise, less than half of them did it at the recommended frequency (≥ 3 days in a week and at least 30 minutes for each session). This was in consonance with a previous report by Iloh et al.,Citation25 in 2014, who found the adherence rate to physical activity to be the lowest among the domains of lifestyle modification assessed among adult hypertensive Nigerians with essential hypertension in Eastern Nigeria.

The practice of regular exercise has been shown to be suboptimal among hypertensives in NigeriaCitation25,32 and other parts of the world.Citation16 The obvious benefits of moderate-intensity exercise on BP control are documentedCitation16,34 but concerns regarding adherence are growing.Citation25,32 The suboptimal practice of exercise among the respondents in this study suggests that primary care physicians must inculcate the habit of counselling hypertensive patients on the importance of regular exercise. They must also prescribe physical exercise in the same way as anti-hypertensive medications are prescribed. Also, patients must be followed up to make sure that they practise the prescribed physical activity in order to improve blood pressure control.

Conclusion

The percentage of hypertensive respondents with optimal BP control in this study is low, despite one-third of them having health insurance. Physicians should pay more attention to patients who are likely to have poor BP control. This includes being male, having coexisting diabetes mellitus, poor adherence to medication and poor clinic attendance. Furthermore, lifestyle modification as well as a 100% health insurance package for all levels of hypertensive care should be extended to the informal sector of the economy in order to increase access to quality health care.

Limitations

The following limitations were considered in this study. The limitations imposed by the self-reported measure of adherence are acknowledged by the authors. Second, the related data cannot address issues of causal relationship between blood pressure control and its determinants as a result of the cross-sectional design of the study. Furthermore, some of the patients that were labelled as having primary hypertension might indeed have secondary hypertension. This could be avoided if facilities were readily available for extensive investigations. Lastly, the prevalence of diabetes mellitus did not include undiagnosed respondents.

Declaration

Ethical approval for the study was obtained from the Federal Medical Centre, Abeokuta ethical and research committee. Funding for the research was provided by the authors. There is no conflict of interest, as the authors have no financial or personal relationships that may have inappropriately influenced them in writing this paper.

Key messages

Health care providers should reflect on various factors affecting blood pressure control. This will help in the establishment of strategies with patients and family members so that control of blood pressure in patients with hypertension can be optimal and cost-effective.

Acknowledgement

The authors appreciate Mr Ogunlana of the Department of Physiotherapy, FMC, Abeokuta for his technical support. Special thanks are offered to all colleagues in Department of Family Medicine, FMCA, Abeokuta for their contributions during the preparation of this work. The authors also wish to express their gratitude to the Head of Department of Medical Records, FMC, Abeokuta.

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Appendix I

Informed Consent

Dear Sir/Madam,

I hereby seek your consent to participate in this research.

I am a doctor at the Department of Family Medicine of a secondary care health centre. I intend to find out the pattern of blood pressure control and determine the factors affecting control of blood pressure in patients with essential hypertension with a view to improving control of blood pressure among patients with essential hypertension.

If you consent, a questionnaire will be administered to you followed by a physical examination. The procedure will last for about 20 minutes. The result of this project will be presented in a West African College of Physicians dissertation project.

Your participation is entirely of your own free will and you can withdraw from the study at any time you like without explanation. Refusal to participate in the study will not affect your treatment in any way. You have the right to refuse to answer any question you don’t want to answer.

Please note that any information collected will remain confidential. Your name will not be attached to any published results. My supervising consultants and I will have access to the data.

Kindly indicate your decision by signing in the space below.

Thank you.

………………………… ………………….. Date and signature or thumbprint Date and signature or thumbprint

of participant of witness

Appendix II

Questionnaire

RESEARCH PROFORMA ON AN APPRAISAL OF BLOOD PRESSURE CONTROL AND ITS DETERMINANTS AMONG PATIENTS WITH PRIMARY HYPERTENSION SEEN AT A PRIMARY CARE SETTING IN WESTERN NIGERIA.

Good day Sir/Madam,

Thank you for consenting to participate in this study. This research is about finding out the factors influencing blood pressure control. It will help us serve you better. Your cooperation is needed to truthfully answer the questions below. All information will be strictly confidential and it will take only a few minutes. Thank you.

Serial Number.........................................

Hospital number......................................

Date ........................................................

A. SOCIO-DEMOGRAPHIC VARIABLES

1) Age………..… years

2) Gender:(i) Male(ii) Female

3) Marital status:(i) Single(ii) Married(iii) Divorced

(iv) Separated(v) Widowed

4) Religion:(i) Islam(ii) Christianity(iii) Traditional belief

(iv) Others

5) Ethnic group:(i) Yoruba (ii) Hausa (iii) Igbo (iv) Others

6) Marriage type:(i) Monogamy(ii) Polygamy

7) If polygamy, number of wives …………………..

8) Household size …………………..

B. SOCIO-ECONOMIC DATA

9) Level of education completed by subject: (i) No formal education(ii) Primary

(iii) Secondary (iv) Tertiary

10) What do you do for a living? …………………..?

11) What is your average monthly income……….....?

C. SOCIAL HISTORY

12) Are you currently smoking?(i) Yes(ii) No

13) Are you currently drinking alcohol? (i) Yes (ii) No

14) Do you exercise?(i) Yes(ii) No

15) If yes to question 26, which of these exercises do you do?

(i) Cycling (ii) Basketball (iii) Jogging (iv) Swimming(v) Soccer

(vi) Walking (fast)(vii) Others

16) How frequently do you do the exercise stated above?

(i) Every two weeks (ii) Once per week (iii) 1–2 days/ week (iv) ≥ 3 days/ week

17) How long does the exercise last? (i) < 30minutes (ii) > 30 minutes

D. CLINICAL FACTORS

18) How long ago were you diagnosed as hypertensive? ...................................

19) How long ago have you been on an antihypertensive? ……………………..

20) How often do you take your drugs? (i) Regularly (ii) Not regularly

21) If not regularly, why?

(i) Often forget (ii) High cost of drugs (iii) Religious practices and cultural beliefs

(iv) Poor knowledge of disease and ignorance on long-term treatment (v) Use of alternative

therapy (vi) Adverse drug reaction (vii) Too many drugs (viii) Inadequate access to

medical care

22) Do you keep your clinic appointment? (i) Yes (ii) No

23) If no, why?

(i) Tight job schedule (ii) Long distance (iii) Financial reasons (iv) Other reasons

24) Do you have access to health care insurance? (i) Yes (ii) No

25) Is any member of your family hypertensive? (i) Yes (ii) No (iii) I don’t know

26) If yes, state relationship to you…………………..

27) Do you have diabetes?

28A) Knowledge on hypertension

28B) What is the effect of any of these on blood pressure?

E. PHYSICAL EXAMINATION

29) Systolic blood pressure ……………

30) Diastolic blood pressure……………

31) Waist circumference (cm)…………