Synthesis and characterization of Ag-decorated litchi-like porous Cu/Cu₂O micro/nanoparticles with antibacterial activity

ABSTRACT

Efficient and stable inorganic antibacterial material is highly spotted in antibacterial materials. However, the morphology and grain diameter of conventional inorganic compound antibacterial agent carrier are difficult to control and severely deteriorate antibacterial properties. In this research, using diethylene glycol monomer methyl ether as a pore-forming agent, litchi-like porous micro/nano Cu/Cu₂O composite antibacterial carriers (Car-MNps) with good dispersion and high crystallinity are prepared by a liquid-phase chemical reduction process. Subsequently, we develop a synergistic system of inorganic composite antibacterial materials decorated with silver (Ag/Car-MNps). The microstructures of the antibacterial materials are characterized by means of various techniques, such as X-ray diffraction, scanning electron microscope, transmission electron microscope, X-ray photoelectron spectroscopy, and nitrogen adsorption. The antibacterial activities are evaluated by methods of bacteriostatic zone and minimum inhibitory concentration (MIC). The results show that the micro- and nano-materials of Car-MNPs exhibit high specific surface area characteristics and show attractive bactericidal properties. The MIC values of Ag/Car-MNps against S. aureus and E. coli decrease from 1000 mg/L and 2000mg/L to 125 and 250 mg/L, respectively, in comparison with those of Car-MNps. Our experiments may show novel insights for the development of inorganic compound antibacterial agents.

GRAPHICAL ABSTRACT

KEYWORDS:

• Porous micro- and nano-materials
• liquid-phase chemical reduction
• composite antibacterial agents
• silver decoration
• antibacterial activity

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.

Additional information

Funding

This work was supported by Natural Science Foundation of Guangxi Province [grant number: 2018GXNSFDA294002]; Key Research and Development Program of Guangxi [grant number: GuiKeAB19110032]; National Natural Science Foundation of China [grant number: 62065004]; Guangxi Key Laboratory of Information Materials [grant number: 201010-K].