Advanced search
Publication Cover
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Volume 22, 2021 - Issue 1-2
Submit an article Journal homepage
1,091
Views
5
CrossRef citations to date
0
Altmetric
Short Reports

Validation of the Italian version of self-administered ALSFRS-R scale

Umberto Manera1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy andCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9995-8133
ORCID Icon,
Sara Cabras1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Margherita Daviddi1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Rosario Vasta1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy andORCID Iconhttps://orcid.org/0000-0002-0393-4736
ORCID Icon,
Maria Claudia Torrieri1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Francesca Palumbo1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Alessandro Bombaci1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy andORCID Iconhttps://orcid.org/0000-0002-3961-6780
ORCID Icon,
Maurizio Grassano1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Luca Solero1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Laura Peotta1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Barbara Iazzolino1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and
,
Antonio Canosa1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and;2 SC Neurologia 1U, AOU Città della Salute e della Scienza of Torino, Turin, ItalyORCID Iconhttps://orcid.org/0000-0001-5876-4079
ORCID Icon,
Andrea Calvo1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and;2 SC Neurologia 1U, AOU Città della Salute e della Scienza of Torino, Turin, ItalyORCID Iconhttps://orcid.org/0000-0002-5122-7243
ORCID Icon,
Adriano Chiò1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and;2 SC Neurologia 1U, AOU Città della Salute e della Scienza of Torino, Turin, ItalyORCID Iconhttps://orcid.org/0000-0001-9579-5341
ORCID Icon &
Cristina Moglia1 ALS Centre, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Turin, Italy and;2 SC Neurologia 1U, AOU Città della Salute e della Scienza of Torino, Turin, ItalyORCID Iconhttps://orcid.org/0000-0001-7377-7222
ORCID Icon show all
Pages 151-153 | Received 22 May 2020, Accepted 18 Aug 2020, Published online: 28 Aug 2020
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Objectives

To validate and assess the reliability of the Italian version of self-administered ALSFRS-R, considering patients’ clinical and cognitive features and caregiver’s help. Methods: During the COVID-19 pandemic, by analyzing the results of 70 paired self-administered vs standard telephone-administered ALSFRS-R, we calculated overall score, single item scores, ALSFRS-R domain scores, King’s and MiToS stage inter-rater agreement and reliability using different validated methods. We created the Italian version of self-administered ALSFRS-R following ENCALS recommendation. Results: Correlation between the two scales was 0.94 and no systematic directional bias was found. The intraclass correlation coefficient (ICC) was very high (>0.90) for the vast majority of the considered classification criteria, especially King’s total score (0.96) and MiToS score (0.94). A higher ICC was found when the patients answered the questionnaire with the caregiver’s help (0.95). Conclusions: Online self-administered ALSFRS-R scale is a valid tool to stratify ALS patients into clinical stages and to implement telemedicine monitoring.

Acknowledgements

Our special thanks to Elisa Pesce for the Italian translation of the self-administered ALSFRS-R version. The Italian version is available in Supplementary material.

Disclosure statement

Dr. Manera, Dr. Cabras, Dr. Daviddi, Dr. Vasta, Dr. Torrieri, Dr. Palumbo, Dr. Bombaci, Dr. Grassano, Dr. Solero, Dr. Peotta, Dr. Iazzolino, Dr. Canosa, and Dr. Moglia report no conflicts of interest. Prof. Calvo has received a research grant from Cytokinetics. Prof. Chiò serves on scientific advisory boards for Mitsubishi Tanabe, Roche, Biogen, and Cytokinetics. The sponsor organizations had no role in data collections and analysis and did not participate in writing and approving the manuscript. The information reported in the manuscript has never been reported elsewhere.

Data availability statement

Data will be available upon request by interested researchers.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 478.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.