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Research Articles

Aerobic exercise simultaneous with non-invasive ventilation reduces the length of stay in intensive care in patients with heart failure: a randomised clinical trial

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Pages 176-184 | Received 27 Jan 2023, Accepted 16 Jun 2023, Published online: 05 Jul 2023
 

Abstract

Introduction

Early cardiac rehabilitation using non-invasive ventilation (NIV) and aerobic exercise may reduce the length of hospital stay in patients with heart failure (HF), however, there is still no evidence of this effect on patients in the intensive care unit (ICU).

Objectives

to investigate the effects of aerobic exercise (AE) performed simultaneously with non-invasive ventilation (NIV) on the length of intensive care stay (LICUS) in patients diagnosed with decompensated heart failure (HF) admitted to the intensive care units (ICU).

Methods

Twenty-eight patients admitted to the intensive care unit (ICU) because of decompensation of HF were randomised into two groups: the intervention group (AE + NIV), and a control group. The intervention group’s treatment strategy involved simultaneous AE with NIV daily. The control group performed non-simultaneous AE and NIV daily during their ICU stay. The primary outcome was LICUS. The secondary outcomes were the length of hospital stay, peripheral and respiratory muscle strength, functional status, functional classification, and exercise tolerance.

Results

The mean LICUS was shorter in AE + NIV than in the control group (6.3 ± 4.7 days vs 8.3 ± 3.6 days, respectively; p = 0.015). Secondary outcomes were similar between groups, except for exercise hemodynamics, which was improved in AE + NIV, as showed by the decreased diastolic blood pressure immediately after the exercise tolerance test.

Conclusion

The use of AE simultaneous with NIV reduced the LICUS of patients admitted to the ICU because of decompensated HF. This innovative approach is a promising tool for accelerating ICU discharge during the in-hospital rehabilitation of patients with HF.

Acknowledgements

The authors thank the patients that gently accepted to participate of the study despite their current illness status.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

FUNDACOR- Fundação Pró-Coração.

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