In vivo person specific human body simulation for development and optimisation of surgical methods and materials

ABSTRACT

Simulation technology in mechanical engineering during product development is used routinely to reduce development time, prototypes and development cost. Nevertheless modelling and simulation technology of the human body has been mainly applied to component analysis or crash/accident simulation. The objective of this research is to explore the possibility of reducing human and animal trials for the development and optimisation of surgical methods and materials. To achieve these objectives, an in vivo and person specific simulation model is required. Leaning upon the research involving human being in the mechanical engineering, it was decided to experiment in vivo using a 50th percentile Adult Male. After obtaining ethics approval, a volunteer was selected. Three MRI scans of this volunteer were performed, each covering from the C4 vertebral level to the pubic symphysis; in two composed 3D volumes and each performed under different chest loading conditions. The 3 D MRI dataset was segmented and a Catia CAD-model created. One can manipulate and use this CAD-model derived from a human volunteer like any CAD-model in mechanical engineering. A simulation model is created from the CAD-model and non-linear analysis is carried out. The comparison of simulation results with that of test is good.

KEYWORDS:

• In vivo
• specific
• loading
• MRI
• segmentation
• CAD

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Notes on contributors

Rashid Ahmad

Rashid Ahmad graduated with B.Sc Engineering (UET, Lahore, PAK), 1967; Dipl.-Ing. (TU Darmstadt, W Germany), 1972; Dr.-Ing. (TU Hannover, W Germany), 1974. Experiences in MAN, Nuermberg, W Germany, 1974-1975; The University of Tabriz, Tabriz, Iran, 1975-1976; Consulting Engineering Office Bung, Heidelberg, W Germany, 1976-1977; Ford of Germany, Cologne, W Germany 1977-1982; Ford of Australia, Geelong/ Melbourne, Australia, 1982-1993; BTR Germany, Lindau (B), Germany. 1993 - 2002; Delphi Berlin, Germany, 2002-2005; Boeing, Melbourne office, Australia, 2005 - 2009; Currently Deakin University, Research Academic.

Peter Hodgson

Peter Hodgson Fellow Australian Academy of Technological Sciences and Engineering (ATSE) • Distinguished Professor, Wuhan University of Science and Technology • Fellow of the Institute of Engineers, Australia • DHC, Valenciennes • PhD, University of Queensland, Queensland, Australia • B.Eng. (Hons), Monash University, Melbourne, Australia

Xiao Bo Zhang

Xiao Bo Zhang Associate Professor, M.D.M.S.  FRACS Cardiothoracic Surgeon, Department of Cardiothoracic Surgery, University Hospital Geelong, Barwon Health, Geelong Clinical Associate Professor at Deakin University Mr Zhang was the Director of Cardiothoracic Surgery at University Hospital Geelong for five years and has established a parallel private cardiac surgery service at Saint John of God Geelong Hospital, which successfully launched in 2015. His experience includes formal training at all of Victoria’s major teaching hospitals as well as overseas training in Germany, Canada, China and the USA. He is a Clinical Associate Professor at Deakin University and is a member of the National Steering Committee for the Australian and New Zealand Society of Cardiothoracic Surgeons, the peak professional body for cardiac surgery.

Andrew Whan

Andrew Whan Assoc. Professor Whan was Director of Barwon Medical Imaging from 2008 – June 2018.  Dr Whan also completed a six month sabbatical at University of Oxford in the UK focusing on neuro, paediatric and prostate MRI imaging, sharing the knowledge gained with our local team of consultant radiologists.Dr Whan completed his training at Austin Hospital and was awarded the Gold Medal as the top candidate in the Royal Australian and New Zealand College of Radiologists Fellowship Exam. In 2001, Andrew completed advanced fellowship training at Austin Hospital in MRI and breast imaging before travelling to Perth where he obtained further fellowship training in MRI with a particular focus on musculoskeletal imaging.Andrew is currently an Examiner with the Royal Australian and New Zealand College of Radiologists and an Associate Professor and Tutor at Deakin Medical School, Deakin University.

Kate Negus

Kate Negus graduated with a bachelor degree in Radiography in Melbourne, Australia (RMIT) in February 1992 and joined The Australian Institute of Radiography - AIR (now ASMIRT). She began her MRI training at The Austin Hospital in late 1993. A lecture she gave at an RMIT short course on MRI in 1997 lead to an opportunity to work at a new MRI site being set up at Barwon Medical Imaging at The Geelong Hospital. Kate enjoyed optimizing the upgraded Siemens Avanto fit and Prisma fit systems at University Hospital, Geelong, in 2016-17. She is the current Treasurer of the ANZ chapter of the SMRT and was the Victorian Representative for the ANZ SMRT prior to this. Much of her time is currently spent on organizing the 13^th Annual ANZ SMRT meeting in Melbourne in November 2018.