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Original Articles

Phytochemical Screening and Anthelmintic and Antifungal Activities of Leaf Extracts of Stevia rebaudiana

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Pages 56-63 | Received 19 Oct 2012, Accepted 11 Dec 2012, Published online: 07 Jun 2013
 

Abstract

The aim of this study was to assess the phytochemical screening of various extracts of Stevia rebaudiana leaves. Further, the alcohol and aqueous extracts were subjected to determine their in vitro anthelmintic and antifungal activities against P. posthuma and A. galli earthworms as well as plant pathogenic fungi B. cinerea and F. oxysporum, respectively. The alcoholic and aqueous extracts of S. rebuadiana contained steroids, glycosides, tannis, alkaloids and saponnis like phytochemicals. Both alcoholic and aqueous extracts (25-100 mg/ml) exhibited significant anthelmintic activity at the used concentrations involving determination of paralysis and death time of the tested worms. Also the aqueous and ethanolic extracts (1 mg/disc each) exerted potent antifungal activity as a radial growth inhibition percentage against the tested plant pathogens B. cinerea (64.2 and 67.5 %) and F. oxysporum (65.3 and 73.6 %), whereas the MIC values of the tested extracts were found in the range of 1 to 3 mg/ml.

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