The phenomenological experience of autobiographical memory in patients with behavioral-variant frontotemporal dementia

Abstract

In this study, we offer a comprehensive assessment of the phenomenological experience of patients with behavioral-variant frontotemporal dementia (bvFTD) upon retrieval of autobiographical memory. We invited patients with bvFTD and control participants to retrieve autobiographical memories and rate, for each memory, its phenomenological characteristics. We also analyzed the retrieved memories regarding specificity (i.e., whether the memory described a general or a detailed event). Results demonstrated that, compared to control participants, patients with bvFTD attributed lower levels of reliving, back in time (feeling as if going back in time), remembering, realness, visual imagery, auditory imagery, language, emotion, rehearsal, importance, spatial recall and temporal recall to their memories. Lower autobiographical specificity was also observed in patients with bvFTD compared to control participants. Autobiographical specificity in patients with bvFTD was associated with verbal fluency and verbal episodic memory, but not with phenomenological experience. Although autobiographical memories of patients with bvFTD show low ratings of phenomenological experience, the patients may still enjoy some limited subjective experience during autobiographical retrieval.

Keywords:

• Autobiographical memory
• behavioral-variant frontotemporal dementia
• frontotemporal dementia
• phenomenological experience
• subjective experience

Disclosure statement

The authors have no conflict of interest to declare.

Additional information

Funding

MEH is supported by DISTALZ LABEX, DK is supported by the NIH Intramural Research Program.