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Research Article

Validity and reliability of the Turkish version of the Australian National University-Alzheimer’s Disease Risk Index (ANU-ADRI)

ORCID Icon, , , , , ORCID Icon, ORCID Icon, & ORCID Icon show all
Published online: 25 Jun 2024
 

Abstract

Introduction

There is still a requirement for concise, practical scales that can be readily incorporated into everyday schedules and predict the likelihood of dementia onset in individuals without dementia. This study aimed to assess the reliability of the ANU-ADRI (Australian National University Alzheimer’s Disease Risk Index)-Short Form in Turkish geriatric patients.

Methods

This methodological study involved 339 elderly patients attending the geriatric outpatient clinic for various reasons. The known-group validity and divergent validity were assessed. The ANU-ADRI was administered during the baseline test and again within one week for retest purposes. Alongside the ANU-ADRI, all participants underwent a comprehensive geriatric assessment, including Activities of Daily Living (ADL), mobility assessment (Performance-Oriented Mobility Assessment (POMA) and Timed Up and Go Test), nutritional assessment (Mini Nutritional Assessment (MNA)), and global cognition evaluation (Mini-Mental State Examination (MMSE)).

Results

The scale demonstrated satisfactory linguistic validity. A correlation was observed between the mean scores of the ANU-ADRI test and retest (r = 0.997, p < 0.001). Additionally, there existed a moderate negative linear association between the ANU-ADRI and MMSE scores (r = −0.310, p < 0.001), POMA (r = −0.406, p < 0.001), Basic ADL (r = −0.359, p < 0.001), and Instrumental ADL (r = −0.294, p < 0.001). Moreover, a moderate positive linear association was found between the ANU-ADRI and the Timed Up and Go Test duration (r = 0.538, p < 0.001).

Conclusion

The ANU-ADRI-Short Form was proved as a valuable tool for clinical practice, facilitating the assessment of Alzheimer’s disease risk within the Turkish geriatric population.

Acknowledgements

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. All authors agreed on submission. All authors declare no conflict of interest. The data that support the findings of this study are available from the corresponding author, [A.T.I.], upon reasonable request.

Author contributions

A.T.I designed the study. F.M., A.C.M., K.P., M.S.O, collected the data and worked in the interpretation of the results. B.A.S., was responsible for the statistical analysis. F.M., D.K., E.A.B., S.G., wrote the draft of the paper. A.T.I supervised and made the critical review.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.

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